基于影像的计算流体力学在冠状动脉疾病中的研究进展  

Research progress of image-based computational fluid dynamics in coronary artery diseases

作　　者：乔红艳[1] 张龙江(审校) QIAO Hongyan;ZHANG Longjiang(Department of Medical Imaging,Wuxi Third People Hospital,Wuxi 214000,China;Department of Medical Imaging,Eastern Theater General Hospital)

机构地区：[1]无锡市第三人民医院医学影像科,无锡214000 [2]东部战区总医院医学影像科

出　　处：《国际医学放射学杂志》2019年第6期678-683,共6页International Journal of Medical Radiology

基　　金：国家科技部重点研发计划（2017YFC0113400）

摘　　要：动脉粥样硬化是一种由动脉炎症、血管重塑等多种因素引起的系统性疾病.血流动力学因素在动脉粥样硬化斑块的病理生理变化中具有重要作用.综述血管生物应力的基本概念和剪切应力在斑块进展和破裂中的作用,并重点探究基于影像的计算流体力学的相关进展和在识别高危斑块中的应用,以提高识别未来罪犯斑块的特异性.Atherosclerosis is a systemic disease caused by arterial inflammation,vascular remodeling and other reasons.Hemodynamics play an important role in the pathophysiological changes of atherosclerotic plaques.This review elaborates the basic concepts of vascular biomechanical stress,introduces the role of shear stress in plaque progression and rupture,and highlights the progress of image-based computational fluid dynamics and its application in identifying high-risk plaques,to improve the specificity of identifying future criminal plaques.

关 键 词：冠心病 急性冠状动脉综合征 流体力学 动脉粥样硬化斑块 剪切应力 

分 类 号：R541.4[医药卫生—心血管疾病] R445[医药卫生—内科学]