三伏贴治疗过敏性鼻炎疗效的系统性评价和Meta分析  

Systematic Evaluation and Meta-analysis of the Efficacy of Acupoint Application in the Treatment of Allergic Rhinitis

作　　者：李文婷 芮轶群 吕阳 张金兰 陈燕清 LI Wenting;RUI Yiqun;LV Yang;ZHANG Jinlan;CHEN Yanqing(ShanXi University of Chinese Medicine,Taiyuan 030024,China)

机构地区：[1]山西中医药大学

出　　处：《云南中医学院学报》2019年第2期55-60,共6页Journal of Yunnan University of Traditional Chinese Medicine

基　　金：国家自然科学基金(81202623);山西省卫生计生委科研课题(2017130)

摘　　要：目的系统评价三伏贴治疗过敏性鼻炎的有效性。方法由2名研究者进行文献筛选和文献质量评价,运用RevMan5.3软件对纳入随机对照临床试验(RCT)研究进行Meta分析。结果共纳入9项RCT研究,共871例过敏性鼻炎患者,其中观察组440例,对照组431例。症状积分方面,由于纳入文献较少,且标准并不具有统一性,仅进行定性分析。Meta分析结果显示,单纯三伏贴组总有效率明显优于西药组(RR=1.15,95%CI[1.03,1.27],P=0.01),三伏贴联合西药组总有效率优于西药组评分(RR=1.32,95%CI[1.17,1.48],P<0.00001),三伏贴联合针刺组总有效率优于单纯针刺组(RR=1.30,95%CI[1.17,1.44],P<0.00001)。结论三伏贴治疗过敏性鼻炎患者具有较好的临床效果。本系统评价因受纳入文献质量、数量和试验设计欠规范等限制,上述结论仍需高质量、大样本、试验设计严格、多中心的研究加以验证。Objective To evaluate the effectiveness of acupoint application in the treatment of allergic rhinitis.Methods Two researchers searched for literatures and evaluated quality,using RevMan5.3 software for Meta-analysis included in RCT studies.Results A total of 9 RCT studies were included in the study,totaling observation group 440 cases and the matched group 431 cases.In the symptom score,due to the small number of included literatures and the lack of uniformity of standards,only qualitative analysis was conducted.According to the statistical analysis,the results showed that the total effective acupoint application group was superior to conventional western medicine group(RR=1.15,95%CI[1.03,1.27],P=0.01),acupoint application group combined with western medicine group was superior to conventional western medicine group(RR=1.32,95%CI[1.17,1.48],P<0.00001),acupoint application group combined with acupuncture group was superior to single acupuncture group(RR=1.3,95%CI[1.17,1.44],P<0.00001).Conclusion Acupoint application therapy can significantly improve patients'mental state and quality of life and prognosis.However,the evaluation of this system is limited by the quality and quantity of the included literature and the non-standard experimental design,and more high-quality,the conclusions still need be verified by a strict multi-center study with high-quality and large sample design.

关 键 词：穴位贴敷 过敏性鼻炎 随机对照 系统评价 META分析 

分 类 号：R246.81[医药卫生—针灸推拿学]