稳定期COPD患者骨骼肌消耗及影响因素分析  

Skeletal muscle wasting among stable COPD patients: the influencing factors

作　　者：韩燕霞[1] 钮美娥[1] 吴振云[2] 阚亚楠 耿敏 许诺 钱红英[2] Han Yanxia;Niu Mei'e;Wu Zhenyun;Kan Yanan;Geng Min;Xu Nuo;Qian Hongying(Nursing Department,The First Affiliated Hospital of Soochow University,Suzhou 215006,China)

机构地区：[1]苏州大学附属第一医院护理部,江苏苏州215006 [2]苏州大学附属第一医院呼吸科,江苏苏州215006 [3]苏州大学护理学院

出　　处：《护理学杂志》2019年第21期28-31,共4页Journal of Nursing Science

基　　金：苏州市科技发展计划(民生科技)项目(SS201865);苏州市科教兴卫青年科技项目(KJXW2016009)

摘　　要：目的探讨稳定期慢性阻塞性肺疾病(COPD)患者骨骼肌消耗及其影响因素。方法采用便利抽样法选取141例门诊稳定期COPD患者作为调查对象,采用一般资料调查表、COPD病情综合评价相关指标、生物电阻抗测量、COPD生活质量测评表对其进行调查。结果COPD患者去脂体重指数水平为(17.19±1.94)kg/m2,发生骨骼肌消耗44例(31.20%);骨骼肌消耗组患者生活质量总分及日常生活能力、焦虑心理因子得分与正常组比较,差异有统计学意义(P<0.05,P<0.01);Logistic回归分析显示,体重指数、FEV1%及呼吸困难评分是患者发生骨骼肌消耗的影响因素(P<0.05,P<0.01)。结论稳定期COPD患者存在较严重的骨骼肌消耗,对患者生活质量产生影响,骨骼肌消耗的发生与低体质量、严重气流受限及呼吸困难有关。Objective To explore the influencing factors of skeletal muscle wasting among stable COPD Patients.Methods A total of 141 regular clinic-visiting patients with stable COPD were recruited by convenience sampling method and evaluated,with the general questionnaire,comprehensive evaluation indicators,bioelectrical impedance analysis(BIA),and the COPD Quality of Life(QOL)Questionnaire.Results The average of fat free mass index was(17.19±1.94)kg/m2 through BIA.The incidence rate of skeletal muscle wasting was 31.20%(44 cases).There were significant differences in scores of QOL,ADL,and anxiety between the skeletal muscle wasting and non-wasting groups(P<0.05,P<0.01).Logistic regression analysis revealed that BMI,FEV1%and dyspnea scores were the factors affecting skeletal muscle was-ting(P<0.05,P<0.01).Conclusion Skeletal muscle wasting,which is associated with low body mass,severe airflow restriction,and dyspnea,is serious in stable COPD patients,and it affects the quality of life of patients.

关 键 词：慢性阻塞性肺疾病 稳定期 骨骼肌消耗 影响因素 生活质量 抑郁心理 焦虑 呼吸困难 

分 类 号：R473.5[医药卫生—护理学]