间氨基苯酚的合成新方法  

A New Synthetic Process for m-Aminophenol

作　　者：陆晟 张龙 王晗[1] 沈永嘉[2] LU Sheng;ZHANG Long;WANG Han;SHEN Yongjia(College of Chemical Engineering,Shanghai University ofEngineering and Technology Shanghai,201620;Institute of Fine Chemicals,East China University of Science and Technology,Shanghai,200237)

机构地区：[1]上海工程技术大学化学化工学院,上海201620 [2]华东理工大学精细化工研究所,上海200237

出　　处：《上海染料》2019年第5期3-5,共3页Shanghai Dyestuffs

摘　　要：开发了一种合成间氨基苯酚的新方法,以间二硝基苯与过量的苯甲醇在碳酸钾的存在下发生亲核取代反应,生成的产物(间硝基苄基苯酚)不分离,直接转移到压力釜中,经催化氢化-裂解反应得到间氨基苯酚,同时副产甲苯.整个反应过程不需要用水,故没有废水的问题.A new synthetic process for m-aminophenol was developed.The nucleophilic substitution reaction of m-dinitrobenzene with excess benzyl alcohol in the presence of potassium carbonate was conducted,whose product(m-nitrobenzyl phenol)without separation was transferred directly to a autoclave to afford m-aminophenol by catalytic hydrogenation-cracking reaction together with by-product toluene.The whole reaction processes do not need water,so there is no waste water problem.

关 键 词：间二硝基苯 间硝基苄基苯酚 催化氢化-裂解 间氨基苯酚 

分 类 号：TQ620.4[化学工程—精细化工]