25400例患者四项感染性指标检测结果分析  

Analysis of Four Infectious Indicators in 25400 Patients

作　　者：韩小娟 罗洁 田洪伦 曹方怀 尹科 张丽 何军 HAN Xiaojuan;LUO Jie;TIAO Honglun;CAO Fanghuai;YIN Ke;ZHANG Li;HE Jun(Laboratory Department,Second People's Hospital Guiyang,Guizhou 550004)

机构地区：[1]贵州省第二人民医院检验科,贵州贵阳550004

出　　处：《大医生》2019年第9期169-171,共3页Doctor

摘　　要：目的探讨患者入院前检测四项感染性标志物的必要性。方法选取2016年6月至2018年9月贵州省第二人民医院收治的25400例患者(包括住院和门诊)的乙型肝炎病毒表面抗原(HBsAg)、抗丙型肝炎病毒肝抗体(抗-HCV)、抗梅毒螺旋体抗体(抗-TP)、抗艾滋病病毒抗体(抗-HIV)血清的检测结果进行回顾性分析,以此探究感染性标志物检测的必要性。结果25400例患者四项感染性指标阳性率分别为:HBsAg阳性率5.91%,抗-HCV阳性率0.85%,抗-TP阳性率2.15%,抗-HIV阳性率0.17%;与女性组比较,男性组HBsAg、抗-HCV、抗-TP、抗-HIV四项感染性标志物阳性率增高,差异有统计学意义(P<0.05)。按年龄分成1~30岁组,31~50岁组,>50岁组,三组之间HBsAg、抗-HCV、抗-TP阳性率比较,差异有统计学意义(P<0.05),均为31~50岁组病发率高;抗-HIV阳性率比较,差异无统计学意义(P>0.05)。与综合科比较,精神科患者HBsAg阳性率及四项指标总阳性率显著降低(P<0.001);与住院患者比较,门诊患者HBsAg阳性率及四项指标总阳性率显著升高(P<0.001)。结论开展四项感染性指标检测,有助于及时了解患者情况,对控制院内交叉感染、降低医疗意外发生率、预防医疗纠纷的发生具有重要意义。Objective To explore the necessity of detecting four infectious markers before admission.Methods Serum samples of HBsAg,anti-HCV,anti-Treponema pallidum(anti-TP)and anti-HIV were collected from 25400 patients admitted to the Second People's Hospital of Guizhou Province from June 2016 to September 2018.The results were analyzed retrospectively to explore the necessity of detection of infectious markers.Results The positive rates of four infectious markers in 25400 patients were 5.91%for HBsAg,0.85%for anti-HCV,2.15%for anti-TP and 0.17% for anti-HIV,respectively.Compared with the female group,the positive rates of four infectious markers in the male group were higher(P<0.05).According to age,they were divided into 1-30 years old group,31-50 years old group and >50 years old group.There were significant differences in the positive rates of HBsAg,anti-HCV and anti-TP among the three groups(P<0.05),both of which were higher in 31-50 years old group,while there was no significant difference in the positive rates of anti-HIV(P>0.05).Compared with general department,the positive rate of HBsAg and the total positive rate of four indicators in psychiatric patients were significantly lower(P<0.001),and the positive rate of HBsAg and the total positive rate of four indicators in outpatient patients were significantly higher(P<0.001).Conclusion The detection of four infectious indicators is helpful to timely understand the patient's condition,and is of great significance in controlling hospital cross-infection,reducing the incidence of medical accidents and preventing medical disputes.

关 键 词：乙型肝炎病毒表面抗原 抗丙型肝炎病毒抗体 抗艾滋病病毒抗体 抗梅毒螺旋体抗体 感染 

分 类 号：R51[医药卫生—内科学]