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作 者:费娟[1] FEI Juan(Department of Oncology,Nantong Hospital of Traditional Chinese Medicine,Nantong,Jiangsu Province,226000 China)
机构地区:[1]南通市中医院肿瘤科
出 处:《中外医疗》2019年第29期161-163,共3页China & Foreign Medical Treatment
摘 要:目的 探讨艾灸治疗胃肠道肿瘤癌因性疲乏患者的临床效果。方法 方便选取2016年11月-2018年11月南通市中医院收治的胃肠道肿瘤癌因性疲乏患者116例,按随机数字表法分为试验组(n=58)、对照组(n=58)。对照组予以常规对症支持治疗,试验组于常规对症支持治疗基础上采取艾灸治疗,均治疗1个月。对比两组治疗前、治疗1个月后癌因性疲乏程度、自然杀伤(NK)细胞、CD3+/人类白细胞抗原DR(HLADR+)水平及治疗1个月后生活质量改善率。结果 试验组治疗1个月后癌因性疲乏程度较治疗前降低,且低于对照组(u1=4.384、P1=0.000,u2=3.765、P2=0.000);试验组治疗1个月后NK细胞、CD3+/HLADR+水平分别为(24.28±6.09)%、(8.64±3.17)%均较治疗前的(18.47±5.61)%、(6.32±2.85)%提高,且高于对照组的(18.90±5.14)%、(7.28±2.65)%(t1=5.344、P1=0.000,t2=4.145、P2=0.000,t3=5.141、P3=0.000,t4=2.507、P4=0.014);试验组治疗1个月后生活质量改善率37.93%高于对照组20.69%(χ^2=4.161、P=0.041)。结论 应用艾灸治疗胃肠道肿瘤癌因性疲乏患者可显著降低患者癌因性疲乏程度,提升免疫功能,改善生活质量。Objective To investigate the clinical effect of moxibustion on patients with gastrointestinal cancer caused by cancer.Methods From November 2016 to November 2018,116 patients with gastrointestinal cancer caused by gastrointestinal cancer in Nantong Traditional Chinese Medicine Hospital were convenient randomly divided into experimental group(n=58)and control group(n=58).The control group received routine symptomatic supportive treatment.The experimental group was treated with moxibustion on the basis of conventional symptomatic supportive treatment,and all were treated for 1 month.The levels of cancer-induced fatigue,natural killer(NK)cells,CD3+/human leukocyte antigen DR(HLADR+),and quality of life improvement after 1 month of treatment were compared before treatment and 1 month after treatment.Results The degree of cancer-induced fatigue in the experimental group was lower than that before treatment,and was lower than that in the control group(u1=4.384、P1=0.000,u2=3.765、P2=0.000).NK cells were treated in the experimental group 1 month later.The levels of CD3+/HLADR+were(24.28±6.09)%and(8.64±3.17)%,respectively,which were higher than(18.47±5.61)%and(6.32±2.85)%before treatment,and higher than that of the control group(18.90±5.14)%,(7.28±2.65)%(t1=5.344、P1=0.000,t2=4.145、P2=0.000,t3=5.141、P3=0.000,t4=2.507,P4=0.014);quality of life improved after 1 month of treatment in the experimental group was 37.93%higher than that of the control group(20.69%)(χ^2=4.161,P=0.041).Conclusion The application of moxibustion in the treatment of patients with gastrointestinal cancer due to fatigue can significantly reduce the degree of cancer-related fatigue,improve immune function and improve quality of life.
关 键 词:胃肠道肿瘤 癌因性疲乏 艾灸 免疫功能 生活质量
分 类 号:R246[医药卫生—针灸推拿学]
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