中药颗粒剂足浴辨治早期糖尿病足150例  

Treatment of 150 Cases of Early Diabetic Foot with Chinese Medicine Granule Foot Bath

作　　者：周思锋 张金明[1] 徐洪亮[1] 高玉飞 朱正花 顾林 ZHOU Si-feng;ZHANG Jin-ming;XU Hong-liang;GAO Yu-fei;ZHU Zheng-hua;GU Lin(Department of Endocrinology,Rudong Hospital of Traditional Chinese Medicine,Nantong,Jiangsu Province,226400 China)

机构地区：[1]如东县中医院内分泌科

出　　处：《中外医疗》2019年第29期170-173,共4页China & Foreign Medical Treatment

基　　金：南通市市级科技计划(HS149140)

摘　　要：目的 分析中药颗粒剂足浴辨治早期糖尿病足的临床效果。方法 随机选取2015年7月-2018年3月该院收治的150例早期糖尿病足病患者作为研究对象,采用1:1随机分组方式将其分成两组,所有患者均给予糖尿病基础治疗,治疗组采用中药颗粒剂足浴辨治方式及前列地尔10μg加入生理盐水100 m L中静脉滴注,对照组仅用单纯前列地尔静脉滴注,剂量方法同前,疗程4周。观察两组临床疗效、治疗前后左右股动脉内径和峰值流速、治疗前后症状轻重分级。结果 治疗组患者总有效率81.33%高于对照组患者66.67%,差异有统计学意义(χ^2=4.192,P=0.040<0.05)。治疗组患者治疗后左右股动脉内径、峰值流速(8.42±0.14)cm、(8.56±0.24)cm、(79.26±3.14)cm/s、(76.83±3.86)cm/s优于对照组患者(8.39±0.11)cm、(8.51±0.13)cm、(82.16±4.62)cm/s、(80.08±4.12)cm/s,差异有统计学意义(P<0.05),治疗组患者及对照组患者治疗后左右股动脉内径、峰值流速优于治疗前,差异有统计学意义(P<0.05)。治疗组患者治疗后皮温(-)例数、足背动脉(-)例数、疼痛(-)例数、感觉(-)例数为66例、40例、48例、33例优于对照组患者52例、22例、32例、14例,差异有统计学意义(P<0.05),治疗组患者及对照组患者治疗后症状轻重分级状况优于治疗前,差异有统计学意义(P<0.05)。结论 中药足浴和前列地尔治疗0级糖尿病足安全有效。Objective To analyze the clinical effect of traditional Chinese medicine granules in the treatment of early diabetic foot.Methods 150 patients with early diabetic foot disease admitted to the hospital from July 2015 to March 2018 were randomly selected and divided into two groups by 1:1 randomization.All patients were given basic treatment for diabetes.The treatment group was treated with traditional Chinese medicine granules foot bath and 10μg of prostaglandil in 100 mL of normal saline.The control group was only intravenously infused with alprostadil.The dose was the same as before,and the course of treatment was 4 weeks.The diameter and peak flow velocity of the left and right femoral artery before and after treatment,and the severity of symptoms before and after treatment.Results The total effective rate of the treatment group was 81.33%higher than that of the control group(66.67%),The differents was statistically significant(χ^2=4.192,P=0.040<0.05).The diameter and peak flow velocity of the left and right femoral artery(8.42±0.14)cm,(8.56±0.24)cm,(79.26±3.14)cm/s,(76.83±3.86)cm/s were better in the treatment group than in the control group(8.39±0.1)cm,(8.51±0.13)cm,(82.16±4.62)cm/s,(80.08±4.12)cm/s.The differents was statistically significant(P<0.05).The diameter and peak flow velocity of the left and right femoral artery after treatment in the treatment group and the control group were better than those before treatment.The differents was statistically significant(P<0.05).The number of skin temperature(-),the number of dorsal artery(-),the number of pain(-),and the number of sensory(-)(66 case,40 case,48 case,33 case)were better in the treatment group.The patients in the control group(52 cases,22 cases,32 cases,14 cases)had statistical significance.The differents was statistically significant(P<0.05).The patients in the treatment group and the control group were better than the pre-treatment symptoms after treatment,The differents was statistically significant(P<0.05).Conclusion Chinese medicine f

关 键 词：糖尿病足 中药足浴 前列地尔 临床观察 

分 类 号：R248[医药卫生—中医临床基础]