阿替洛尔对急性冠脉综合征合并心律失常患者的临床疗效  

Clinical Effect of Atenolol on Patients with Acute Coronary Syndrome and Arrhythmia

作　　者：信彬彬[1] 王军利[1] XIN Binbin;WANG Junli(The First Clinic of Heilongjiang Armed Police Corps Hospital,Harbin,Heilongjiang 150010,China)

机构地区：[1]武警黑龙江省总队医院第一门诊,黑龙江哈尔滨150010

出　　处：《大医生》2019年第11期119-120,共2页Doctor

摘　　要：目的探讨阿替洛尔对急性冠脉综合征合并心律失常的临床疗效。方法选择2017年1月至2019年1月武警黑龙江省总队医院收治的126例急性冠脉综合征合并心律失常患者,随机分为两组,每组63例。两组患者均给予常规治疗,实验组加用阿替洛尔治疗,比较两组治疗效果、炎性因子水平[高敏C反应蛋白(hsCRP)、白介素-6(IL-6)、肿瘤坏死因子(TNF-α)]、心功能分级差异。结果实验组总有效率明显高于对照组(95.24%vs.73.02%,P<0.05);治疗后hsCRP、IL-6、TNF-α较对照组明显下降(P<0.05);实验组心功能Ⅲ级、Ⅳ级发生率较对照组明显降低(P<0.05)。结论针对急性冠脉综合征合并心律失常患者应用阿替洛尔治疗效果显著,可抑制炎性反应,改善心功能,值得推广应用。Objective To investigate the effect of atenolol on acute coronary syndrome with arrhythmia.Methods A total of 126 patients with acute coronary syndrome and arrhythmia admitted to our hospital from January 2017 to January 2019 were randomized into 2 groups,63 cases per group.Patients in both groups were given routine treatment,and the experimental group was treated with atenolol additionally.The treatment effects,inflammatory factor levels[high-sensitivity C-reactive protein(hsCRP),interleukin-6(IL-6),tumor necrosis factor(TNF-α)],and cardiac function grading were compared between the two groups.Results The total effective rate of the experimental group was higher than that of the control group(95.24%vs.73.02%,P<0.05).After treatment,hsCRP,IL-6,and TNF-αwas significantly lower than the control group(P<0.05).The cardiac function ofⅢand IV grades in the experimental group was significantly lower than those in the control group(P<0.05).Conclusion The application of atenolol in patients with acute coronary syndrome and arrhythmia was effective by inhibiting inflammatory reaction and improving cardiac function.It was worthy of popularization and application.

关 键 词：阿替洛尔 急性冠脉综合征 心律失常 

分 类 号：R54[医药卫生—心血管疾病]