磁共振HASTE序列和TRUE-FISP序列在胎儿唇腭裂诊断中的应用  

Application of magnetic resonance HASTE and TRUE-FISP sequences in diagnosis of fetal cleft lip and palate

作　　者：周清[1] 张鹤[1] 尹璇 刘雪芬[1] 王雪珍[1] 张国福[1] ZHOU Qing;ZHANG He;YIN Xuan;LIU Xuefen;WANG Xuezhen;ZHANG Guofu(Obstetrics&Gynecology Hospital of Fudan University,Shanghai 200011,China)

机构地区：[1]复旦大学附属妇产科医院

出　　处：《磁共振成像》2019年第11期817-820,共4页Chinese Journal of Magnetic Resonance Imaging

基　　金：上海市自然科学基金(编号：19ZR1407200)~~

摘　　要：目的评价MRI HASTE序列和TRUE-FISP序列对胎儿唇裂和腭裂畸形的诊断价值。材料与方法选取20例临床提示胎儿唇腭裂畸形的孕妇行MRI扫描。扫描序列采用半傅立叶单激发自旋回波(half-Fourier single-shot turbo spin echo,HASTE)序列和真性快速稳态进动(true fast imaging with steady-state precession,TRUE-FISP)序列。所有图像经2名10年以上MRI诊断经验医师进行阅片。分别对唇腭裂的有无以及图像质量进行评分。结果 20例胎儿产后随访结果,7例为正常胎儿,3例伴有唇裂,均发生在左侧,9例伴有唇腭裂,5例发生在右侧,4例发生在左侧,腭裂程度不明确,1例唇裂伴腭全裂。针对唇裂:医师1在HASTE和TRUE-FISP两个序列的诊断准确性分别为100%和95%;医师2诊断准确性为分别为95%和95%。针对腭裂:医师1在HASTE和TRUEFISP序列的诊断准确性分别为85%和90%;医师2诊断准确性为分别为85%和100%。扫描失败的层面:HASTE序列中6个扫描关键层面缺失。TRUE-FISP序列中12个扫描关键层面缺失。结论 MRI扫描时合理运用序列可以更好地地评价胎儿唇腭裂畸形。Objective: The purpose of this study was to evaluate the value of MRI HASTE and TRUEFISP sequences in diagnosis of cleft lip and cleft palate respectively. Materials and Methods: Half-Fourier single-shot turbo spin echo(HASTE) and true fast imaging with steadystate precession(TRUE-FISP) scanning of 20 pregnant women with cleft lip and palate deformity were analyzed. All images were reviewed by two obstetric MRI diagnosis doctors with 10-year experience. The presence of cleft lip and palate and image quality were scored. Results: Postpartum follow-up results of 20 fetuses showed that 7 were normal fetuses, 3 had cleft lip, 9 had cleft lip and palate, 5 cases occurred on the right side and 4 cases on the left side. The degree of cleft palate was not clear, and 1 had cleft lip and cleft palate. For cleft lip, the diagnostic accuracy of reader 1 in HASTE and TRUE-FISP sequences was 100% and 95% respectively, and that of reader 2 was 95% and 95% respectively. For cleft palate, the diagnostic accuracy of reader 1 in HASTE and TRUE-FISP sequences was 85% and 90% respectively, and that of reader 2 was 85% and 100% respectively. Scanning failure planes: 6 key layers of HASTE sequence were missing. Twelve key scan layers were missing in TRUE-FISP sequence. Conclusions: Coupled with appropriate protocols, MRI scans could evaluate fetal cleft lip and palate with higher accuracy.

关 键 词：唇裂 腭裂 胎儿 磁共振成像 

分 类 号：R445.2[医药卫生—影像医学与核医学] R782.21[医药卫生—诊断学]