2018年乌鲁木齐市急性呼吸道感染患儿中5种病毒感染情况调查  

Etiological survey on five respiratory viruses among pediatric patients with acute respiratory infections in Urumqi in 2018

作　　者：樊旭成[1] 何华 高枫[1] 韩志国[1] 薛娜[1] 房师松[2] 汤晓璇 Fan Xucheng;He Hua;Gao Feng;Han Zhiguo;Xue Na;Fang Shisong;Tang Xiaoxuan(Division of Infectious Diseases,Urumqi Center for Disease Control and Prevention,Urumqi 830026 China;Division of Microbiological Laboratory,Shenzhen Center for Disease Control and Prevention,Shenzhen 518055 China;School of Public Health,Xinjiang Medical University,Urumqi 830011,China)

机构地区：[1]乌鲁木齐市疾病预防控制中心传染病防治科,830026 [2]深圳市疾病预防控制中心微生物检验科,518055 [3]新疆医科大学公共卫生学院流行病与卫生统计学教研室,乌鲁木齐830011

出　　处：《国际病毒学杂志》2019年第5期312-315,共4页International Journal of Virology

基　　金：国家自然科学基金(81871631);乌鲁木齐市科学技术计划重点实验室项目(H171313001)。

摘　　要：目的分析2018年乌鲁木齐市急性呼吸道感染患儿咽拭子样本中多种呼吸道病毒的检测结果,了解呼吸道病毒的病原学特征和流行规律.方法利用多重实时荧光PCR的方法,对2018年1月-12月的1935份呼吸道感染患儿咽拭子样本进行5种常见呼吸道病毒的核酸检测,并分析核酸阳性率在不同季节、年龄、性别以及区域分布的差异.结果1935份样本中,5种呼吸道病毒核酸阳性率为50.34%.其中,流感病毒核酸阳性率最高,为37.73%;其次为副流感病毒,核酸阳性率为8.32%;另外3种病毒核酸阳性率均为1%左右.5种病毒核酸阳性率在不同性别、年龄、季节的分布差异均具有统计学意义.结论流感病毒、副流感病毒为乌鲁木齐市儿童呼吸道病毒感染的主要病原体.相较于7~12岁的儿童,3岁以下儿童更容易感染呼吸道病毒,应重点加强婴幼儿阶段儿童的呼吸道病原监测.Objective To analyze the detection results of respiratory viruses in throat swab samples from pediatric patients with acute respiratory infections in Urumqi in 2018,so as to understand the etiological and epidemiological characteristics of the respiratory viruses.Methods Multiple real time fluorescent PCR was used to detect nucleic acids of five common respiratory viruses in 1935 throat swab samples of pediatric patients with respiratory infections collected from January to December,2018.The difference of the positive rates in different seasons,ages,genders,and regions was compared.Results For the 1935 samples,the positive rate of five respiratory viruses was 50.34%.The positive rate of influenza virus nucleic acids(37.73%)was the highest,followed by parainfluenza virus(8.32%).The positive rates of nucleic acids of the other three viruses were about 1%.The differences in the distributions of positive rates of nucleic acids for the five viruses in different genders,ages and seasons were statistically significant.Conclusions Influenza virus and parainfluenza virus were the main pathogens of respiratory tract viral infections among children in Urumqi.The respiratory viral infections among children under 3 years old were more common than that in children of 7-12 years old.The surveillance of respiratory viruses for infants should be strengthened.

关 键 词：呼吸道感染 呼吸道病毒 病原学 

分 类 号：S85[农业科学—兽医学]