心电向量图联合血浆脑钠肽及HbAlc检测对慢性肺心病的诊断价值研究  

Diagnostic Value Research of Vectorcardiogram Combined with Plasma Brain Natriuretic Peptide and HbAlc for Chronic Cor Pulmonale

作　　者：王凤翠[1] 崔彦博[1] WANG Feng-cui;CUI Yan-bo(Jilin City Central Hospital,Jilin,Jilin,132001)

机构地区：[1]吉林市中心医院

出　　处：《智慧健康》2019年第30期114-115,共2页Smart Healthcare

摘　　要：目的对脑钠肽在慢性肺心病的质量过程中会起到的作用以及进一步的具体应用所具有的使用价值进行探讨。方法对某医院在某时间内收治的66为慢性肺心病患者的质量情况进行观察测试,测量开始之前之后对于患者收缩末期的血浆脑钠肽进行测量比对,这一过程中重点监测比值,肺动脉收缩压,动脉血氧分压,动脉血氧分压,1s用力呼气量和肺活量。同时,70名健康体检医师被用作对照组。结果经过检测可以看出患者病情加重的时候血浆当中脑钠肽的浓度为(4665.34±139.56)ng/L,而相对的患者病情不严重的时候血浆中脑钠肽浓度为(148.65±12.32)ng/L.差异有统计学意义。慢性肺心病患者治疗4周后血浆脑利钠肽浓度为(356.28±68.75)ng/L,差异有统计学意义。结论血浆脑利钠肽是反映CPHD急性加重的敏感指标。脑钠尿肽浓度对CPHD急性加重期的诊断和治疗具有较高的指导价值。Objective To explore effect and further application value of brain natriuretic peptide(BNP) in treatment of chronic cor pulmonale(CPD). Methods Observe and test 66 cases chronic cor pulmonale patients admitted to a hospital during some certain period. Before and after test, measure and compare plasma brain natriuretic peptide. During the process, monitor ratio, pulmonary artery systolic pressure, arterial partial pressure of oxygen, arterial partial pressure of oxygen, 1 s forced expiratory volume and vital capacity. At the same time, 70 cases health examiners were treated as control group. Results Test showed, plasma concentration of brain natriuretic peptide was(4665.34±139.56) ng/L when patient’s condition was aggravated, while that was(148.65±12.32) ng/L when condition was not serious. Difference was statistically significant. Plasma concentration of brain natriuretic peptide of chronic cor pulmonale patients 4 weeks after treatment was(356.28±68.75) ng/L, difference was statistically significant. Conclusion Plasma brain natriuretic peptide is a sensitive index reflecting acute exacerbation of CPHD, whose concentration has high guiding value in diagnosis and treatment of acute exacerbation of CPHD.

关 键 词：心电向量 血浆脑钠肽 慢性肺心病 

分 类 号：R54[医药卫生—心血管疾病]