2015年-2017年深圳市福田区腹泻病毒监测结果分析  

Analysis of viral diarrhea surveillance in Futian District,Shenzhen during 2015-2017

作　　者：申红卫 曾华书[2] 欧泳萱[2] 许玉成 柯君岩[3] 陈浩川 SHEN Hong-wei;ZENG Hua-shu;OU Yong-xuan;XU Yu-cheng;KE Jun-yan;CHEN Hao-chun(Shenzhen Hospital,Southern Medical University,Shenzhen,Guangdong 518110,China)

机构地区：[1]南方医科大学深圳医院,广东深圳518110 [2]深圳市福田区疾病预防控制中心,广东深圳518040 [3]深圳大学生命与海洋科学学院,广东深圳518052

出　　处：《中国卫生检验杂志》2019年第21期2561-2563,2570,共4页Chinese Journal of Health Laboratory Technology

基　　金：深圳市科研计划项目(JCYJ20160428152017475);深圳市卫计委项目(201602009);福田区卫生公益性科研项目(FTWS2016049,FTWS2016050);深圳市福田区卫生公益性科研项目(FTWS2019067)

摘　　要：目的了解深圳市福田区腹泻患者中腹泻病毒的流行特征以及变化趋势。方法收集2015年-2017年哨点医院确诊腹泻患者的基本信息和粪便标本,采用反转录-聚合酶链反应(RT-PCR)方法检测诺如病毒、轮状病毒、肠道腺病毒、星状病毒,对结果进行统计分析。结果1972份标本中4种腹泻病毒总的检出率为21.2%(418/1972),其中2015年、2016年、2017年的检出率分别为23.4%、18.1%、22.8%。腹泻病毒检测阳性率依次分别为诺如病毒11.6%(228/1972)、轮状病毒7.7%(151/1972)、星状病毒2.1%(41/1972)、肠道腺病毒1.3%(26/1972)。11月-次年1月的检出率最高,为27.3%;5岁以下儿童检出率为34.4%,显著高于其他年龄组(P<0.05)。结论腹泻病毒在本地区长期流行,其中诺如病毒和轮状病毒是主要的病原体。5岁以下儿童是主要的感染人群,11月-次年1月是感染的高峰时间。Objective To define the epidemiological features and the change trend of viral diarrhea in Futian District,Shenzhen.Methods Stool samples and demographic data of acute diarrheal patients were collected from the sentinel hospitals from 2015 and 2017.Stool samples were tested for norovirus(NV),rotavirus(RV),enteric adenovirus(EAdV),and astrovirus(A stV)using reverse transcription polymerase chain reaction(RT-PCR)method,and the results were analyzed using SPSS 19.0.Results Among the 1972 samples,the detection rate of 4 diarrhea virus was 21.2%(418/1972).The detection rate in 2015,2016,and 2017 was 23.4%,18.1%,and 22.8%.The detection rate for NV,RV,EAdV,and AstV was 11.6%(228/1972),7.7%(151/1972),2.1%(41/1972),and 1.3%(26/1972).The highest detection rate was found from November through January(21.3%),and that in children aged less than 5 years old was 34.4%,significantly higher than other age groups(P<0.05).Conclusion Diarrhea viruses have been prevalent in this area for a long period,with NV and RV being the predominant organisms.Children aged 0-4 years old are the main group at risk and November-January is the time of infection peak.

关 键 词：腹泻 病毒 流行病学 监测 

分 类 号：R725.[医药卫生—儿科]