沙美特罗氟替卡松联合噻托溴铵治疗慢性阻塞性肺疾病的临床效果  

Clinical effect of Salmeterol Fluticasone combined with Tiotropium in the treatment of chronic obstructive pulmonary disease

作　　者：王陈 WANG Chen(The Third Department of Internal Medicine,Guixi People's Hospital of Jiangxi Province,Guixi 335400,China)

机构地区：[1]江西省贵溪市人民医院内三科

出　　处：《中国当代医药》2019年第30期75-77,共3页China Modern Medicine

摘　　要：目的观察并分析沙美特罗氟替卡松联合噻托溴铵治疗慢性阻塞性肺疾病(COPD)的临床效果。方法选取2016年7月~2018年8月我院收治的100例COPD患者作为研究对象,根据随机数字表法分为对照组和观察组,每组各50例。对照组患者采用沙美特罗氟替卡松治疗,观察组患者采用沙美特罗氟替卡松联合噻托溴铵治疗,观察并比较两组患者的临床治疗效果以及肺功能水平。结果两组患者治疗后的最大呼气流量比较,差异无统计学意义(P>0.05);观察组患者治疗后的第1秒用力呼气容积、第1秒用力呼气容积/预计值高于对照组,差异有统计学意义(P<0.05);观察组患者的临床治疗总有效率高于对照组,差异有统计学意义(P<0.05)。结论采用沙美特罗氟替卡松联合噻托溴铵治疗COPD患者,可以有效改善患者的肺功能,提高患者的临床治疗效果。Objective To observe and analyze the clinical effect of Salmeterol Fluticasone combined with Tiotropium bromide in the treatment of chronic obstructive pulmonary disease(COPD).Methods One hundred patients with COPD treated in our hospital from July 2016 to August 2018 were selected as the study subjects.According to the random number table method,they were divided into the control group and the observation group,with 50 cases in each group.The control group was treated with Salmeterol Fluticasone.The observation group was treated with Salmeterol Fluticasone combined with Tiotropium.The clinical effects and lung function levels of the two groups were observed and compared.Results There was no significant difference in the maximum expiratory flow between the two groups after treatment(P>0.05).The first second forced respiratory volume and the first second forced respiratory volume/predicted value in the observation group were higher than those in the control group after treatment,and the differences were statistically significant(P<0.05).The total effective rate of clinical treatment in the observation group was higher than that in the control group,and the difference was statistically significant(P<0.05).Conclusion Salmeterol Fluticasone combined with Tiotropium in the treatment of patients with COPD can effectively improve the lung function of patients and improve the clinical treatment effect.

关 键 词：慢性阻塞性肺疾病 沙美特罗氟替卡松 噻托溴铵 临床效果 

分 类 号：R563[医药卫生—呼吸系统]