大梯度强磁场抗磁物质悬浮的生物学效应及其应用  

Biological Effects and Application of Diamagnetic Levitation by Large Gradient High Magnetic Tield

作　　者：杨建成[1,3,4] 杨鹏飞 杨周岐[1,3] 王哲[1,3] 吕毅[1,3] 谢丽[1,3] 尹大川[1,3] 商澎[2,3] Yang Jiancheng;Yang Pengfei;Yang Zhouqi;Wang Zhe;Lyu Yi;Xie Li;Yin Dachuan;Shang Peng(Research&Development Institute in Shenzhen,Northwestern Polytechnical University,Shenzhen Guangdong 518057,China)

机构地区：[1]西北工业大学生命学院,陕西西安710072 [2]西北工业大学深圳研究院,广东深圳518057 [3]西北工业大学空间生物实验模拟技术国防重点学科实验室,陕西西安710072 [4]深圳市龙华区人民医院,广东深圳518109

出　　处：《航天医学与医学工程》2019年第5期377-385,共9页Space Medicine & Medical Engineering

基　　金：国家自然科学基金面上项目(51777171);西北工业大学博士论文创新基金(CX201839)

摘　　要：梯度强磁场是一种特殊的人工稳恒强磁场,抗磁性物质在这种磁场中的特殊位置上可模拟失重效应,即抗磁悬浮。与目前建立的多种模拟失重环境或失重生物学效应的装置与技术相比,抗磁悬浮技术在力学本质上更接近于空间失重环境,且模拟失重的作用时间持久,具有良好的稳定性,更适用于长时间失重环境要求的生物学实验。目前大梯度强磁场下的抗磁悬浮技术在生物学研究中的应用还处于现象揭示及基础研究阶段,有许多科学问题和应用方向值得探索。综述了大梯度强磁场下抗磁物质悬浮对动物、植物、微生物、细胞和生物大分子等影响的研究进展,并对其应用前景进行了展望。The large gradient high magnetic field(LGHMF)is a special artificial high static magnetic field and at a special position within LGHMF,the apparent gravity level of the diamagnetic material can be changed to simulate a weightlessness status called diamagnetic levitation.Compared with other established devices or techniques simulating the weightlessness environment or the biological effects of weightlessness,the diamagnetic levitation technology is closer in mechanics to the real space weightlessness,and it can constantly and steadily maintain the simulated microgravity condition which makes it more suitable for biological experiments exposed to long-term weightlessness condition.However,the application of the diamagnetic levitation technology under LGHMF in biological research is still in the phenomena revealing and fundamental research stages.There are many scientific issues and application directions that are worth exploring.In this paper,the progresses of biological study in the diamagnetic levitation under LGHMF condition,including animals,plants,microorganisms,cells,and biomacromolecules,were reviewed.Moreover,the future application of the diamagnetic levitation technology were prospected.

关 键 词：大梯度强磁场 抗磁物质悬浮 模拟失重 超导磁体 生物学效应 

分 类 号：R85[医药卫生—航空、航天与航海医学]