高烯丙基酰肼氧化/卤胺环化串联反应合成吡唑啉类化合物（英文）  

Synthesis of Pyrazolines by Cascade Oxidation/Halogenoaminocyclization Reaction of Homoallylhydrazides

作　　者：李鹏飞 黄丹凤[1] 杨天宇[1] 邓周斌 王克虎[1] 王君姣 苏瀛鹏[1] 胡雨来[1] Li Pengfei;Huang Danfeng;Yang Tianyu;Deng Zhoubin;Wang Kehu;Wang Junjiao;Su Yingpeng;Hu Yulai(College of Chemistry and Chemical Engineering,Northwest Normal University,Lanzhou 730070)

机构地区：[1]西北师范大学化学化工学院

出　　处：《有机化学》2019年第10期2920-2929,共10页Chinese Journal of Organic Chemistry

基　　金：Project supported by the National Natural Science Foundation of China(Nos.21662030,21861033)~~

摘　　要：探索了以N-碘代丁二酰亚胺(NIS)作为卤化试剂,通过高烯丙基酰肼化合物的串联氧化/卤胺环化反应合成吡唑啉类化合物.该方法反应条件温和,不需要添加剂,以良好的收率得到吡唑啉类化合物.An efficient cascade oxidation/halogenoaminocyclization reaction of homoallylhydrazides with N-halogensuccinimide was developed without addition of other additives under mild reaction conditions to provide pyrazolines.Under the optimized conditions,a variety of highly substituted pyrazoline derivatives were obtained.

关 键 词：氧化/卤胺环化 吡唑啉 高烯丙基酰肼 N-卤代丁二酰亚胺 

分 类 号：O62[理学—有机化学]