多孔ZnO/羟基磷灰石生物复合材料的制备与性能  

Fabrication and properties of porous ZnO/hydroxyapatite biocomposites

作　　者：朱斌 何远怀[1] 孟增东[2] 张玉勤[1] ZHU Bin;HE Yuanhuai;MENG Zengdong;ZHANG Yuqin(School of Materials Science and Engineering,Kunming University of Science and Technology,Kunming 650093,China;Department of Orthopedics,First People’s Hospital of Yunnan Province,Kunming 650032,China)

机构地区：[1]昆明理工大学材料科学与工程学院,昆明650093 [2]云南省第一人民医院骨外科,昆明650032

出　　处：《复合材料学报》2019年第11期2637-2643,共7页Acta Materiae Compositae Sinica

基　　金：国家自然科学基金(31860264)

摘　　要：利用放电等离子烧结技术制备多孔ZnO/羟基磷灰石(HA)生物复合材料,研究不同纳米ZnO含量对ZnO/HA复合材料微观结构、孔隙特征、力学性能、矿化和降解性能的影响。结果表明:烧结后ZnO/HA复合材料主要由HA相和ZnO相组成;随着ZnO含量提高,多孔ZnO/HA复合材料孔隙率缓慢增大,抗压强度略有减小,弹性模量变化不大;多孔ZnO/HA复合材料的孔隙率>40%,孔径在50~500μm之间,抗压强度>148MPa,弹性模量为6.5GPa左右,能够满足骨修复材料的要求;模拟人工体液中矿化和降解实验表明,多孔ZnO/HA复合材料浸泡7天后表面开始形成大量类骨磷灰石层,且随着ZnO含量增加,磷灰石形成能力明显增强而降解速率加快。The porous ZnO/hydroxyapatite(HA)biological composites were prepared by spark plasma sintering(SPS)technology.The effects of different nano ZnO contents on the microstructure,pore characteristics,mechanical properties,mineralization and degradation of the ZnO/HA composites were studied.The results show that the sintered ZnO/HA composites are mainly composed of HA phases and ZnO phases.With increasing of ZnO content,the porosity of the ZnO/HA composites increases slowly,the compressive strength decreases slowly,and the elastic modulus does not change much.The ZnO/HA composites have the porosity>40%,pore diameter of 50-500μm,compressive strength>148 MPa,elastic modulus about 6.5 GPa,which can meet the requirements of bone repair materials.The mineralization and degradation experiments in simulated artificial body fluids show that a large number of osteoid apatite layers are formed on the surface of the ZnO/HA composite after soaking for 7 days.Furthermore,the apatite formation ability of the ZnO/HA composites is significantly enhanced and the degradation rate of the composites is increased with increasing of ZnO content.

关 键 词：多孔羟基磷灰石 ZNO 放电等离子烧结 力学性能 磷灰石形成能力 

分 类 号：TB332[一般工业技术—材料科学与工程]