1990年至2017年中国人群矽肺的疾病负担分析  

Analysis on disease burden of silicosis in Chinese population from 1990 to 2017

作　　者：朱晓俊 牛东升[1] 王鸿飞 肖培[3] 王艳华 余悦[2] 丁晓文 殷鹏 李婕[4] 李珏[1] 周脉耕 李涛[2] ZHU Xiao-jun;NIU Dong-sheng;WANG Hong-fei;XIAO Pei;WANG Yan-hua;YU Yue;DING Xiao-wen;YIN Peng;LI Jie;LI Jue;ZHOU Mai-geng;LI Tao(Beijing Institute of Occupational Disease Prevention and Treatment,Beijing 100093,China)

机构地区：[1]北京市职业病防治研究院,北京100093 [2]中国疾病预防控制中心职业卫生与中毒控制所,北京100050 [3]北京协和医学院研究生院,北京100730 [4]中国疾病预防控制中心慢性非传染性疾病预防控制中心,北京100050

出　　处：《中国工业医学杂志》2019年第5期346-351,共6页Chinese Journal of Industrial Medicine

基　　金：国家重点研发计划(项目编号:2018YFC1315303)

摘　　要：目的分析1990-2017年中国人群矽肺的疾病负担水平及其变化趋势。方法利用全球疾病负担2017年(GBD 2017)研究结果和数据,分析1990-2017年中国人群矽肺的疾病负担状况并与全球人群进行比较。按年份、年龄、性别分析中国人群矽肺的发病数、死亡数、伤残调整寿命年(DALY)、过早死亡损失寿命年(YLL)、伤残损失寿命年(YLD);同时采用2000-2025年世界人口的平均年龄结构作为标准人口计算中国和全球人群尘肺病的标化发病率、标化死亡率、标化DALY率、标化YLL率、标化YLD率。计算2017年与1990年的变化幅度,分析疾病负担指标的变化。结果 2017年中国人群因矽肺造成的DALY为166 134人年,占中国人群因尘肺病造成DALY (247 619人年)的67. 1%,占中国总DALY (371 485 307人年)的0. 045%,在293种疾病中排名第171位,较1990年(190位)上升了19位;占全球人群因矽肺造成DALY (260 584人年)的63. 8%,在195个国家和地区中排名第1位。2017年中国人群矽肺的发病数、死亡数、DALY分别为15 380例、6 468例、166 134人年,较1990年分别增长69. 6%、15. 2%、2. 1%,增幅均高于全球水平;2017年中国人群矽肺的标化发病率、死亡率、DALY率分别为0. 79/10万、0. 34/10万、8. 32/10万,分别较1990年下降21. 7%、48. 8%、50. 8%。中国人群矽肺的发病数、死亡数、DALY在≥45岁进入高发状态,分别为14 616例(95. 0%)、6 147例(95. 0%)、149 871人年(90. 2%);2017年发病年龄和死亡年龄的中位数分别为67. 3岁、68. 3岁,较1990年分别延长2. 9岁、3. 3岁。结论中国在矽肺防治方面取得了积极成果,但中国人群矽肺所致的疾病负担近年仍有上升趋势,占中国人群尘肺病和全球人群矽肺所致疾病负担的较大比重。应采取措施遏制矽肺的早发病、早死亡,加强健康管理,提高生命质量。Objective To analyze the disease burden of silicosis in Chinese population and its trend from 1990 to 2017.Methods The data of Global Burden of Disease study 2017( GBD 2017) was used for analyzing the disease burden of silicosis in Chinese population from 1990 to 2017 and compared with the result from global analysis in the same period according to year,age and gender,the indicators including incidence number,death number,disability-adjusted life years( DALY),years of life lost( YLL),and years lived with disability( YLD). The average age structure of world population from 2000 to 2025 was used as the standard population to calculate the standardized morbidity,standardized mortality,standardized DALY rate,standardized YLL rate and standardized YLD rate of silicosis in both China and global population. The percentage change for these indicators were compared between 2017 and 1990. Results In 2017,the DALY due to silicosis in Chinese population was 166 134 person years,accounting for 67. 1% of the DALY due to pneumoconiosis in Chinese population( 247 619 person years),accounting for 0. 045% of the total DALY of China( 371 485 307 person years),it ranked 171 out of 293 diseases in China,it moved up by 19 places compared to 1990( 190),that accounted for 63. 8% of the DALY of global population due to silicosis( 260 584 person years),ranking 1 st among 195 countries and regions. The incidence number,death number,DALY number of silicosis in Chinese population of 2017 were 15 380 cases,6 468 cases and 166 134 person years,that increased by 69. 6%,15. 2% and 2. 1% respectively,compared with that of 1990,the growth rate is higher than the global level. The standardized morbidity,mortality and DALY rate of silicosis in Chinese population were 0. 79/100 000,0. 34/100 000 and 8. 32/100 000,which decreased by 21. 7%,48. 8% and 50. 8% respectively,compared with that of 1990. In 2017,the total incidence number,death number and DALY number of silicosis in Chinese population entered a high incidence state when people over 45 years

关 键 词：矽肺 疾病负担 伤残调整寿命年(DALY) 

分 类 号：R135.2[医药卫生—劳动卫生]