多种缺血性心脑血管疾病检测指标的比较  

Comparison of detection indices for various ischemic cardiovascular and cerebrovascular diseases

作　　者：黄超[1] 程秀丽 于海淼 张飚[1] 朱彧[1] 杨萍[1] 孙丽莎 HUANG Chao;CHENG Xiu-li;YU Hai-miao;ZHANG Biao;ZHU Yu;YANG Ping;SUN Li-sha(Department of Clinical Laboratory,Tianjin Huanhu Hospital,Tianjin 300350,China;Tianjin Medical University General Hospital)

机构地区：[1]天津市环湖医院检验科,天津300350 [2]天津医科大学总医院

出　　处：《中国城乡企业卫生》2019年第11期26-30,共5页Chinese Journal of Urban and Rural Enterprise Hygiene

摘　　要：目的探讨缺血性心脑血管疾病某些指标的变化差异及临床意义,为临床筛查高危人群及防治提供可靠依据。方法选取2012年3-9月天津医科大学总医院收治的缺血性心脑血管病患者187例,按疾病类型分为心绞痛组46例、急性心肌梗死组43例、脑缺血组48例、脑梗死组50例;50例健康人为正常对照组。观察在缺血性心脑血管疾病中Hcy、hs-CRP、血脂、凝血功能的变化。结果心绞痛组和急性心肌梗死组Hcy、hs-CRP、TG、D-Dimer明显高于对照组;且急性心肌梗死组Hcy、hs-CRP、D-Dimer明显高于心绞痛组;脑缺血组和脑梗死组Hcy、hs-CRP、TC、TG、LDL-C、DDimer明显高于对照组;且脑梗死组Hcy、hs-CRP、D-Dimer明显高于脑缺血组;缺血性心血管病组和缺血性脑血管病组HDL-C都低于对照组,差异均有统计学意义(P<0.05)。结论无论是缺血性心血管疾病还是缺血性脑血管疾病Hcy、hs-CRP、TG、D-Dimer都明显升高,HDL-C明显降低。缺血性心血管病组hs-CRP升高幅度高于缺血性脑血管病组,而缺血性脑血管病组中Hcy升高幅度高于缺血性心血管病组。Objective To investigate the changes and clinical significance of some indexes in ischemic cardiovascular disease and ischemic cerebrovascular disease,to provide reliable basis for clinical screening high-risk populations prevention and treatment.Methods One hundred and eighty-seven patients with ischemic cardiovascular disease or ischemic cerebrovascular disease admitted to Tianjin Medical University Grneral Hospital from March to September 2012 were selected and divided into angina pectoris group(46 cases),acute myocardial infarction group(43 cases),cerebral ischemia group(48 cases),cerebral infarction group(50 cases) according to the type of disease,and 50 healthy persons were enrolled into control group.To observe the changes in Hey,hs-CRP,blood lipid,blood coagulation in ischemic cardiovascular and cerebrovascular diseases.Results In angina pectoris group and acute myocardial nfarction group,the Hey,hs-CRP,TG,D-Dimer levels were higher than those in the control group;in acute myocardial nfarction group,the Hey,hs-CRP,D-Dimer levels were higher than those in the angina pectoris group;in cerebral ischemia group and cerebral infarction group,the Hey,hs-CRP,TC,TG,LDLC,D-Dimer levels were higher than those in the control group;in cerebral infarction group,the Hey,hsCRP,D-Dimer levels were higher than those in the cerebral ischemia group;in ischemic cardiovascular disease group and ischemic cerebrovascular disease group,the HDL-C levels were lower than that in the control group.The differences were statistically significant(P<0.05).Conclusion Both in ischemic cardiovascular disease and ischemic cerebrovascular disease,the levels of Hey,hs-CRP,TG,D-Dimer were significantly increased,the level of HDL-C was significantly decrease.The increase of hs-CRP in ischemic cardiovascular disease group was higher than that in ischemic cerebrovascular disease group,while the increase of Hey in ischemic cerebrovascular disease group was higher than that in ischemic cardiovascular disease group.

关 键 词：同型半胱氨酸 超敏C-反应蛋白 血脂 凝血 缺血性心血管病 缺血性脑血管病 

分 类 号：R446.11[医药卫生—诊断学]