不同年龄段老年肺部感染患者营养及免疫状态分析  

Analysis of nutritional and immune status of elderly patients with pulmonary infection among different age groups

作　　者：石继英 艾玉 韩惠丽 SHI Jiying;AI Yu;HAN Huili(Department of Internal Medicine,The Second Charity Hospital of Henan Province,Jiaozuo 454000,China)

机构地区：[1]河南省第二慈善医院内科

出　　处：《右江医学》2019年第10期784-788,共5页Chinese Youjiang Medical Journal

摘　　要：目的探讨不同年龄段老年肺部感染患者的营养状态。方法以2016年9月~2018年10月收治的157例老年肺部感染患者作为研究对象,根据年龄段不同分为三组,低段组(60~70岁)62例,中段组(71~80岁)54例,高段组(>80岁)41例。采用简易营养评价精法(MNA-SF)对三组患者的营养状态进行评价和比较,并分析营养状态与生化指标的相关性。结果三组患者在营养不良、免疫功能低下以及营养不良合并免疫功能低下的发生率差异上均有统计学意义(P<0.001),两两比较显示,中段组、高段组的发生率相比低段组明显增高,而高段组营养不良发生率明显高于中段组(P<0.01);三组患者白蛋白(Alb)、低密度脂蛋白(LDL)、血红蛋白(Hb)水平差异有统计学意义(P<0.05);中段组、高段组Alb和LDL水平相比低段组明显降低(P<0.05),中段组和高段组间差异无统计学意义(P>0.05);中段组、高段组Hb水平明显低于低段组(P<0.05),高段组Hb水平明显低于中段组(P<0.05);各年龄段组CD8^+、CD4^+/CD8^+水平差异有统计学意义(P<0.001)。Pearson相关分析显示,患者MNA-SF评分与血Alb、LDL、Hb水平均呈正相关(r=0.410、0.215、0.187,P<0.05或0.01)。结论老年肺部感染患者营养不良以及免疫功能低下发生率较高,且随着年龄的增长其发生营养不良合并免疫功能低下的可能性越大,通过早期检测血液相关营养和免疫功能指标可对其营养和免疫功能状态进行筛查,以便及早有效地实施干预措施。Objective To investigate the nutritional status of elderly patients with pulmonary infection in different age groups.Methods 157 elderly patients with pulmonary infection admitted to hospital from September,2016 to October,2018 were selected as the subjects of study.They were divided into three groups according to age:62 patients in youngage group(60 to 70 years old),54 patients in middle age group(71 to 80 years old),and 41 patients in old age group(>80 years old).Short-form mini-nutritional assessment(MNA-SF)was used to evaluate and compare the nutritional status of the three groups,and correlation between nutritional status and biochemical indexes was analyzed.Results The differencein the incidence of malnutrition,low immune function,and malnutrition combined with immune deficiency among the three groups was statistically significant(P<0.001).Pairwise comparison showed that the incidence of malnutrition in the middle age group and the old age group was significantly higher than that in the low old group,and the incidence of malnutrition in the old age group was significantly higher than that in the middle age group(P<0.01).The differences in albumin(Alb),low density lipoprotein(LDL)and hemoglobin(Hb)levels among the three groups were statistically significant(P<0.05).The levels of Alb and LDL in the middle age group and the old age group were significantly lower than those in the low age group(P<0.05),and the differences between the middle age group and the old age group were not statistically significant(P>0.05).The levels of Hb in the middle age group and the old age group were significantly lower than that in the low age group(P<0.05),and that in the old age group was significantly lower than that in the middle age group(P<0.05).There were statistically significant differences in the levels of CD8^+,CD4^+/CD8^+ among all age groups(P<0.05).Pearson correlation analysis showed that MNA-SF score was positively correlated with blood Alb,LDL and Hb levels(r=0.410,0.215,0.187,P<0.05 or 0.01).Conclusion The incide

关 键 词：老年 肺部感染 营养状态 

分 类 号：R563.1[医药卫生—呼吸系统]