纯母乳喂养婴儿嗜酸粒细胞性结肠炎1例并文献复习  

EOSINOPHILIC COLITIS IN EXCLUSIVELY BREAST-FED INFANTS: A CASE REPORT AND LITERATURE REVIEW

作　　者：禹定乐[1] 蔡华波[1] 江贤萍[1] YU Ding-le;CAI Hua-bo;JIANG Xian-ping(Shenzhen Children's Hospital,Guangdong Shenzhen,518038)

机构地区：[1]深圳市儿童医院

出　　处：《承德医学院学报》2019年第6期462-464,共3页Journal of Chengde Medical University

摘　　要：目的:提高对婴儿嗜酸粒细胞性胃肠炎病因、诊断与治疗的认识.方法:报告1例纯母乳喂养婴儿嗜酸粒细胞性结肠炎的临床资料,并结合相关文献进行复习.结果:49日龄男性患儿,纯母乳喂养,有过敏性疾病家族史,因腹泻、湿疹、吐奶、浮肿就诊,伴营养不良、腹水、贫血、低蛋白血症、外周血嗜酸性粒细胞升高及总IgE升高,结肠黏膜病理示嗜酸粒细胞浸润.予饮食回避(停母乳,改喂氨基酸奶粉),并予激素治疗,病情明显好转.结论:嗜酸粒细胞性胃肠炎的临床表现缺乏特异性,诊断困难时需结合过敏性疾病史,尽早完善肠镜、肠黏膜病理检查;查找过敏原时,母乳亦不容忽视,及时予以饮食回避,治疗效果好.Objective:To raise awareness of pathogeny,diagnosis and treatment of eosinophilic gastroenteritis in infants.Methods:The clinical data of one eosinophilic colitis infant with exclusively breast-fed were reported and relevant literature were reviewed.Results:49-day-old male exclusively breast-fed infant who had a family history of allergic diseases,sought a doctor for diarrhea,eczema,vomiting and edema;With malnutrition,ascites,anemia,hypoproteinemia,elevated eosinophils and elevated total IgE in peripheral blood;Pathological examination of the colonic mucosa showed eosinophilic infiltration.The infant improved significantly after treating with diet avoidance(changed breastfeeding to amino acid milk powder)and hormone.Conclusions:The clinical manifestations of eosinophilic gastroenteritis are lack of specific,the clinical doctors should combine the history of allergic diseases and improve the pathological examination of enteroscopy and intestinal mucosa as soon as possible when it is difficult to diagnose.When looking for allergens,breast milk should not be ignored;Diet avoidance should be given in time and the therapuetic effect is better.

关 键 词：蛋白丢失性肠病 嗜酸粒细胞性胃肠炎 嗜酸粒细胞性结肠炎 食物过敏 治疗 

分 类 号：R725.7[医药卫生—儿科]