正常人前臂桡骨数字X射线骨密度测量结果:全国流行病学调查  

Bone mineral density of forearm using digital X-ray densitometry in normal Chinese population:national epidemiological survey

作　　者：应奇峰 余卫[3] 尹香君[4] 张骏 陈锦平 李志新[4] 王临虹 夏维波[6] YING Qi-feng;YU Wei;YIN Xiang-jun;ZHANG Jun;CHEN Jin-ping;LI Zhi-xin;WANG Lin-hong;XIA Wei-bo(Center of Osteoporosis,Hangzhou Medical School People's Hospital,Hangzhou 310014,China;Center of Osteoporosis,Zhejiang Provincial People's Hospital,Hangzhou 310014,China;Department of Radiology,Peking Union Medical College Hospital,Chinese Academy of Medical Science&Peking Union Medical College,Beijing 100730,China;The National Center for Chronic and Noncommunicable Disease Control and Prevention,the Chinese Center for Disease Control and Prevention,Beijing100050,China;Department of Orthopedics,Zhejiang Provincial People's Hospital,Hangzhou 310014,China;Department of Endocrinology,Peking Union Medical College Hospital,Peking Union Medical College&Chinese Academy of Medical Science,Beijing 100730,China)

机构地区：[1]杭州医学院附属人民医院骨质疏松诊疗中心,杭州310014 [2]浙江省人民医院骨质疏松诊疗中心,杭州310014 [3]中国医学科学院北京协和医学院北京协和医院放射科,北京100730 [4]中国疾病控制中心慢性非传染性疾病预防控制中心,北京100050 [5]浙江省人民医院骨科,杭州310014 [6]中国医学科学院北京协和医学院北京协和医院内分泌科,北京100730

出　　处：《中华骨质疏松和骨矿盐疾病杂志》2019年第5期468-473,共6页Chinese Journal Of Osteoporosis And Bone Mineral Research

摘　　要：目的分析全国流调中数字X射线测量正常人群前臂桡骨骨密度的结果及其特点。方法收集全国12个流调点4982例正常受试志愿者行数字X射线测量前臂桡骨骨密度的测量结果。桡骨测量部位和感兴趣区为非优势侧前臂桡骨远端1/3处。其中男性2110人,平均年龄(54.8±14.2)岁(20~89岁);女性2872人,平均年龄(55.5±13.0)岁(20~89岁)。结果前臂桡骨骨密度峰值均位于30~40岁年龄组,男性骨峰值(0.990±0.118)g/cm^2,显著高于女性骨峰值(0.844±0.100)g/cm 2(P<0.001);峰值后,随年龄组的增加而下降,女性各年龄组的下降率均高于男性,特别是50~60岁年龄组女性骨密度下降最为明显(12.87%/10年)。结论前臂X线骨密度检测系统用于此次流调时的测量结果可反映正常人群前臂桡骨骨密度、骨密度随年龄变化及老年人群骨密度不同程度下降的状况。Objective To analyze the outcomes and characteristics of bone mineral density(BMD)of forearm using digital X-ray densitometry in the epidemiological survey.Methods BMD at forearm was measured in a total of 4982 normal Chinese population with average age of(54.8±14.2)years old(20-89 years old)for males and(55.5±13.0)years old(20-89 years old)for females.Results Peak bone mass of both gender was in the group of 30-40 years old,which was significantly higher in the males(0.990±0.118)g/cm^2 than females(0.844±0.100)g/cm 2(P<0.001).From that on,BMD of forearms decreased in both groups along with increasing age.Females lost their BMD faster than males,with the peak in the group of 50-60 years old(12.87%/10 years).Conclusions Our study provides a database of normal forearm BMD losing speed in Chinese population using digital X-ray densitometry.The outcomes demonstrated the age-related changes in both genders.The modality could be considered as an alternative method for the detection and evaluation of BMD in clinics with its advantages of simplicity and feasibility.

关 键 词：数字X射线骨密度检测系统 骨密度 前臂 流行病学调查 

分 类 号：R681[医药卫生—骨科学]