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作 者:张燕燕[1] 刘屹[1] ZHANG Yanyan;LIU Yi(Department of Radiology,The First Hospital,China Medical University,Shenyang 110001,China)
机构地区:[1]中国医科大学附属第一医院放射科
出 处:《中国医科大学学报》2019年第11期1020-1023,共4页Journal of China Medical University
基 金:国家自然科学基金(81471719)
摘 要:准确评价肝脏病变患者的肝功能储备是肝脏病变治疗前的重点和难点。目前常见的肝功能评估方法主要有以血液生化指标为基础的Child-Turcotte-Pugh评分和终末期肝病模型(MELD)评分系统、吲哚青绿(ICG)排泄试验、计算机体层摄影(CT)或核磁共振成像(MRI)肝脏体积测量、肝脏去唾液酸糖蛋白受体(ASGPR)功能显像技术和采用肝脏可摄取的钆类磁共振造影剂评价肝功能。其中,前2种方法是以化验检查方法为主的肝脏功能评价方法,只能进行肝脏总体功能的评价,而后3种方法是以影像学检查方法为主的肝脏功能评价方法,可以进行肝脏分段功能的评价。Preoperative assessment of reserved liver function is important for patients indicated to undergo partial hepatectomy. Several methods have been commonly used to assess reserved liver function,including Child-Turcotte-Pugh scale score and the model for end-stage liver disease based on biochemical indexes of the blood,indocyanine green elimination test result,liver volume assessment on computed tomography(CT) and magnetic resonance imaging(MRI),positron-emission tomography/CT scans showing asialoglycoprotein receptor expression,and contrast-enhanced MRI scans showing hepatocyte uptake. The first two methods can assess only whole liver function because they are based on the biochemical indexes of the blood. The other three methods can assess segmental liver function because they are based on medical imaging methods.
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