深圳地区女性流动人群HPV预防性疫苗接种意愿调查及影响因素分析  

Survey on attitude of HPV vaccination for cervical cancer prevention among female migrant population in Shenzhen area

作　　者：林威 刘植华 王月云 袁世新 吴波 张建明 陈斌 LIN Wei;LIU Zhi-hua;WANG Yue-yun;YUAN Shi-xin;WU Bo;ZHANG Jian-ming;CHEN Bin(Affiliated Shenzhen Maternity and Child Healthcare Hospital,Southern Medical University,Shenzhen 518028,China)

机构地区：[1]深圳市妇幼保健院,南方医科大学附属深圳妇幼保健院,保健部,广东深圳518028 [2]深圳市妇幼保健院,南方医科大学附属深圳妇幼保健院,妇科,广东深圳518028 [3]深圳市妇幼保健院,南方医科大学附属深圳妇幼保健院,妇幼医学研究所,广东深圳518028

出　　处：《现代预防医学》2019年第22期4094-4098,4140,共6页Modern Preventive Medicine

基　　金：深圳市医疗卫生三名工程(SZSM201612042);深圳市卫生系统科研项目(SZGW2018005)

摘　　要：目的了解深圳地区女性流动人群对HPV及其疫苗的认知情况及疫苗接种意愿和相关影响因素。方法于2015年1-6月在深圳市10个行政区各社康中心对21~60岁女性流动人群进行问卷调查,采用非条件logistic回归模型分析HPV疫苗接种意愿的影响因素。结果本次调查的969名女性流动人群平均年龄为(35.34±8.21)岁,仅有283人(29.2%)听说过人乳头瘤病毒,但548人(56.6%)愿意接种HPV预防性疫苗。不愿意接种的主要原因有:"担心疫苗的安全性"(34.7%)、"疫苗还没有大面积推广"(17.8%)、"疫苗的价格问题"(11.4%)、"对疫苗的效果不信任"(9.7%)、"认为没有患子宫颈癌的危险"(9.7%)及"已经有性生活,接种与否没有什么不同"(8.3%)。多因素logistic回归分析显示,中部地区(OR=1.537,95%CI:1.034~2.286)和东部地区(OR=2.252,95%CI:1.641~3.091)、汉族(OR=1.698,95%CI:1.018~2.832)、高中及以上学历(OR=2.150,95%CI:1.345~3.437)、近6个月性伴数为2个及以上(OR=2.019,95%CI:1.105~3.689)的妇女对HPV疫苗接种意愿更高。结论深圳地区女性流动人群HPV及其疫苗知晓率较低,接种意愿相对较高。地区、民族、受教育程度、性伴数量是影响女性流动人群HPV疫苗接种意愿的相关因素。Objective To investigate the attitude and intention of female migrant population for human papillomavirus(HPV)vaccination and the associated factors in Shenzhen area. Methods Totally 969 female migrant residents were recruited in community health centers of 10 districts by a convenience sampling method. The logistic regression model was applied to analyze possible associated factors. Results The average age of all participants was 35.34±8.21 years old. Despite awareness of HPV(29.2%) was low, willingness to be vaccinated against HPV(56.6%) was relatively high in 969 female migrant residents. The main reasons for unwillingness of vaccination were worrying the safety of vaccine(34.7%), HPV vaccination not being widely accepted(17.8%), the high price of vaccine(11.4%), not trusting the effectiveness of vaccine(9.7%), not considering themselves at risk of cervical cancer(9.7%), and no effect of vaccination when having sexual behaviors(8.3%).Women from central(OR:1.537 and 95% CI:1.034-2.286) and eastern area(OR:2.252 and 95% CI:1.641-3.091), Han ethnicity(OR:1.698 and 95% CI:1.018-2.832), having senior high school degree and above(OR:2.150 and 95% CI:1.345-3.437), and having more than two sexual partners in the past six months(OR:2.019 and 95% CI:1.105-3.689) were associated with higher willingness of HPV vaccination. Conclusions HPV awareness was low among female migrant residents in Shenzhen, but most of them were willing to be vaccinated. Among migrant residents, the associated factors of HPV vaccination acceptability were region, ethnicity, education level, and the number of sexual partners.

关 键 词：子宫颈癌 HPV疫苗 认知 接种意愿 流动人群 

分 类 号：R186[医药卫生—流行病学]