正清风痛宁注射液颈部椎旁注射治疗神经根型颈椎病临床研究  

Clinical Study on Zhengqing Fengtongning Injection by Paravertebral Injection in the Neck for Treatment of Cervical Spondylotic Radiculopathy

作　　者：王中陆 戎宽[3] 蔡萍[1] 匡昱林 匡建军[1] WANG Zhonglu;RONG Kuan;CAI Ping;KUANG Yulin;KUANG Jianjun(Hunan Academy of Chinese Medicine,Changsha 410006,China;Hunan University of Chinese Medicine,Changsha 410208,China;Affiliated Hospital of Hunan Academy of Chinese Medicine,Changsha 410006,China;Shanghai University of Chinese Medicine,Shanghai 200032,China)

机构地区：[1]湖南省中医药研究院,湖南长沙410006 [2]湖南中医药大学,湖南长沙410208 [3]湖南省中医药研究院附属医院,湖南长沙410006 [4]上海中医药大学,上海200032

出　　处：《中国中医药信息杂志》2019年第12期36-39,共4页Chinese Journal of Information on Traditional Chinese Medicine

基　　金：全国名老中医药专家传承工作室建设项目(2013年)

摘　　要：目的观察正清风痛宁注射液颈部椎旁注射治疗神经根型颈椎病的临床疗效。方法采用随机数字表法将100例神经根型颈椎病患者分为对照组和治疗组各50例。对照组予颈椎牵引,治疗组予正清风痛宁注射液颈部椎旁注射,均每日1次,每周5次,连续治疗4周。观察2组临床疗效,比较2组治疗前后症状量表评分、Mc Gill疼痛指数评分,并监测不良反应。结果治疗组总有效率为88.0%(44/50),对照组为58.0%(29/50),2组比较差异有统计学意义(P<0.01)。与本组治疗前比较,2组治疗后不同时点症状量表评分明显升高(P<0.05,P<0.01);2组治疗2、3、4周比较,治疗组症状量表评分高于对照组(P<0.05,P<0.01)。与本组治疗前比较,2组治疗后Mc Gill疼痛指数评分降低(P<0.05);2组治疗后比较,治疗组Mc Gill疼痛指数评分低于对照组(P<0.01)。治疗组不良反应率为4%(2/50),对照组为2%(1/50),2组比较差异无统计学意义(P>0.05)。结论正清风痛宁注射液颈部椎旁注射治疗神经根型颈椎病疗效较好,可明显改善患者临床症状,有效缓解疼痛。Objective To observe the clinical efficacy of Zhengqing Fengtongning Injection by paravertebral injection in the neck for the treatment of cervical spondylotic radiculopathy. Methods Totally 100 patients with cervical spondylotic radiculopathy were divided into control group and treatment group according to random number table method, with 50 cases in each group. The control group received simple cervical traction treatment, and the treatment group received the treatment of Zhengqing Fengtongning Injection by paravertebral injection in the neck. The treatment for both groups was once a day, five times a week, for consecutive 4 weeks. The clinical efficacy of the two groups was observed. The symptom scores, McGill pain index scores of the two groups before and after treatment were compared, and adverse reactions were monitored. Results The total effective rate was 88.0%(44/50) in the treatment group and 58.0%(29/50) in the control group, with statistical significance(P<0.01). Compared with before treatment, the symptom scores of the two groups significantly increased at different time points after treatment(P<0.05, P<0.01);Compared with 2, 3 and 4 weeks after treatment in both groups, the symptom scores of the treatment group were higher than those of the control group(P<0.05, P<0.01). Compared with before treatment, the Mc Gill pain index scores of the two groups decreased after treatment(P<0.05);After treatment, the McGill pain index scores of the treatment group were significantly lower than those of the control group(P<0.01). The adverse reaction rate was 4%(2/50) in the treatment group and 2%(1/50) in the control group, without statistical significance(P>0.05). Conclusion Zhengqing Fengtongning Injection by paravertebral injection in the neck for the treatment of cervical spondylotic radiculopathy has good clinical efficacy, which can significantly improve the clinical symptoms of patients and effectively relieve pains.

关 键 词：正清风痛宁 颈部椎旁注射 神经根型颈椎病 临床研究 

分 类 号：R274.915.31[医药卫生—中西医结合]