天津滨海新区慢性阻塞性肺疾病急性加重期患者病毒感染分析  

Analysis of Virus Infection in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease in Binhai New District of Tianjin

作　　者：邢晓莉[1] 马宏境[1] 张节平 黄少祥[1] XING Xiaoli;MA Hongjing;ZHANG Jieping;HUANG Shaoxiang(Tianjin Fifth Central Hospital,Tianjin 300450,China)

机构地区：[1]天津市第五中心医院

出　　处：《中国医学创新》2019年第30期143-146,共4页Medical Innovation of China

基　　金：天津滨海新区卫生局科技项目(2012BWKY007)

摘　　要：目的:分析天津滨海新区慢性阻塞性肺疾病急性加重期(AECOPD)患者呼吸道病毒感染情况,探讨感染的影响因素。方法:选取2012年12月-2014年12月因急性加重而就诊的200例门诊AECOPD患者,收集患者的临床资料,检测呼吸道病毒,筛选病毒感染的影响因素。结果:200例患者中,67例病毒检测结果阳性,其中鼻病毒检出率最高,单一病毒感染57例,双重病毒感染10例。吸烟指数高、既往1年内急性加重次数多是AECOPD患者发生呼吸道病毒感染的危险因素(P<0.05)。结论:本地区AECOPD患者呼吸道病毒感染以鼻病毒和流感病毒最为常见,吸烟指数高、既往1年内急性加重次数多是AECOPD患者发生呼吸道病毒感染的危险因素。Objective:To analyze the respiratory virus infection in patients with acute exacerbation of chronic obstructive pulmonary disease(AECOPD)in Binhai New District of Tianjin,and to explore the influencing factors of infection.Method:A total of 200 outpatient AECOPD patients who treated for acute exacerbation from December 2012 to December 2014 were enrolled.Clinical data were collected,respiratory viruses were detected,and factors affecting viral infection were selected.Result:Among 200 outpatients,67 cases were positive for virus detection,the detection rate of rhinovirus was the highest,there were 57 cases of single virus infection and 10 cases of double virus infection.High smoking index and the number of acute exacerbations in the past 1 year were risk factors for respiratory virus infection in AECOPD patients(P<0.05).Conclusion:Rhinoviruses and influenza viruses were the common viral pathogen in the patients with AECOPD in Binhai New District of Tianjin.Higher smoking index and the number of acute exacerbations in the past 1 year were risk factors for AECOPD patients to develop virus infection.

关 键 词：慢性阻塞性肺疾病急性加重 呼吸道感染 病毒 聚合酶链反应 

分 类 号：R56[医药卫生—呼吸系统]