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作 者:赵立沙 周冬枝 袁慧[3] 夏欣欣 Zhao Lisha
机构地区:[1]西安市高新区鱼化寨社区卫生服务中心,陕西西安710077 [2]西安交通大学医学部第一附属医院,陕西西安710061 [3]陕西中医药大学第一附属医院,陕西咸阳710000
出 处:《中医临床研究》2019年第29期5-9,共5页Clinical Journal Of Chinese Medicine
摘 要:目的:观察清益宁络方治疗肾小球性血尿的临床疗效及安全性。方法:采用随机对照的方法,将190例,随机分为治疗组102例,对照组88例。对照组行基础治疗及肾素-血管紧张素系统(Renin-Angiotensin System,RAS)阻断治疗,治疗组予以基础治疗及清益宁络方治疗,观察两组治疗前后疗效,尿沉渣红细胞(Red Blood Cell,RBC)计数、中医证候变化及治疗组合并症治疗情况。结果:治疗组的总有效率为89.2%,对照组为77.3%,综合疗效明显优于对照组(P<0.05);尿沉渣RBC数显著低于对照组(P<0.01);中医证候疗效优于对照组(P<0.05)。治疗组中单纯血尿组(A组)疗效优于合并蛋白尿组(B组)、合并高血压病组(C组)(P<0.05)。结论:清益宁络方治疗肾小球性血尿临床疗效确切,保护肾脏功能,改善疾病危险因素,能提高临床治愈率,值得进一步研究与推广。Objective:To observe of the clinical efficacy and safety of the Qingyi Ningluo decoction(清益宁络方)on glomerular hematuria.Methods:190 cases were randomly divided into 102 cases in the treatment group and 88 cases in the control group.The control group was given basic treatment and RAS block treatment.The treatment group was treated with the Qingyi Ningluo decoction more.Results:The total efficiency was 89.2%in the treatment group,and better than 77.3%in the control group(P<0.05).The number of urine sediment RBC was significantly lower than that in the control group(P<0.01).The TCM symptoms in treatment group was better than the control group(P<0.05).The efficacy in group A(simple hematuria)in the treatment group was better than the group B(combine with proteinuria)and group C(combine with hypertension),P<0.05.Conclusion:The Qingyi Ningluo decoction on glomerular hematuria shows an accurate effect,can protect kidney functionm,increase disease risk factors,and increase the cure rate,is worthy of further research and promotion.
分 类 号:R256.5[医药卫生—中医内科学]
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