早产儿喂养不耐受的发生机制研究进展  

Research progress of mechanism of feeding intolerance in premature infants

作　　者：刘艳红[1] 梁桂娟[1] 李远征[1] 闫安平[1] LIU Yanhong;LIANG Guijuan;LI Yuanzheng;YAN Anping(Department of Neonatology,Zhengzhou People's Hospital,Zhengzhou450000,China)

机构地区：[1]郑州人民医院新生儿科

出　　处：《中国现代医生》2019年第30期165-168,共4页China Modern Doctor

摘　　要：早产儿喂养不耐受是影响早产儿生长发育的一个重要原因,目前其发生机制成为研究热点。早产儿喂养不耐受的机制可能与早产儿胃肠道发育不成熟有关,也可能与胃肠道激素如胃动素、胃泌素、血清生长激素释放肽、血管活性肠肽、糖皮质激素等有关。早产儿喂养不耐受还与疾病因素相关,如围生期窒息、胎盘异常、围生期感染、呼吸系统疾病、先天性心脏病、机械通气、早产儿胎龄、体质量、氨茶碱的应用、胃出血等是喂养不耐受发生的危险因素。Feeding intolerance in premature infants is an important factor influencing the growth and development of premature infants.At present,its mechanism has become a hot topic of research.The mechanism of feeding intolerance in premature infants may be related to the immature gastrointestinal development of premature infants,and may also be related to gastrointestinal hormones such as motilin,gastrin,serum growth hormone releasing peptide,vasoactive intestinal peptide and glucocorticoids.Feeding intolerance in premature infants is also associated with disease factors such as perinatal asphyxia,placental abnormalities,perinatal infection,respiratory disease,congenital heart disease,mechanical ventilation,gestational age of preterm infants,body weight,application of aminophylline and gastric bleeding.

关 键 词：早产儿 喂养不耐受 胃泌素 血管活性肠肽 

分 类 号：R722.6[医药卫生—儿科]