吸入用布地奈德混悬液在某儿童医院门急诊使用情况  

Usage Analysis of Budesonide Inhalation Suspension in Outpatient and Emergency Departments of a Children’s Hospital

作　　者：杨珏 李羚[2] 陆燕红 曹丹丹 王燕 陈艳华 YANG Jue;LI Ling;LU Yanhong;CAO Dandan;WANG Yan;CHEN Yanhua(Department of Pharmacy,Wuxi Children’s Hospital,Jiangsu Province,Wuxi 21400.China;Department of Pulmonary,Wuxi Children’s Hospital,Jiangsu Province,Wuxi 21400.China)

机构地区：[1]江苏省无锡市儿童医院药学部,无锡214000 [2]江苏省无锡市儿童医院呼吸内科,无锡214000

出　　处：《医药导报》2019年第12期1656-1661,共6页Herald of Medicine

基　　金：无锡市卫生计生委面上项目(MS201772)

摘　　要：目的回顾性调查某儿童医院门急诊吸入型糖皮质激素布地奈德混悬液的临床使用情况,为保证儿童用药安全,促进临床合理使用吸入型糖皮质激素提供参考。方法随机抽取2018年4月门急诊使用布地奈德混悬液的1000张处方,统计其科室分布、患儿年龄分布、临床诊断分布情况,并对处方的适应证、联合用药情况、用法用量、配伍禁忌等内容分析点评。结果 0~3岁年龄段使用该药的比例达71.60%,属于用药风险较大的人群。不合理处方占63.80%,主要是不适宜处方及超常处方。不适宜处方主要是布地奈德混悬液与复方异丙托溴铵雾化溶液一起配伍使用,占23.00%;超常处方主要为无适应证用药处方,占49.70%。结论布地奈德混悬液在临床中存在无适应证用药现象,临床医生在使用该药时应严格把握适应证,避免无指征用药,以减少患者经济负担及不良反应的发生率。Objective To retrospectively investigate the clinical use of budesonide inhalation suspension in outpatient and emergency departments of a children’s hospital, aiming at providing references for ensuring drug safety in children and promoting the appropriate use of inhaled glucocorticoid in clinic. Methods A total of 1000 prescriptions of budesonide suspension used in outpatient and emergency departments in April 2018 were randomly selected.The distribution patterns of the prescriptions in different clinical departments, age groups and clinical diagnosis were investigated.Indications, drug combinations, dosages, incompatibility and contraindication of the prescriptions were analyzed. Results The group aged 0-3 years accounted for 71.60% of cases who used the drug, which belongs to the population with high risk for the drug use.The inappropriate prescriptions accounted for 63.80%, of which unsuitable prescriptions and extraordinary prescriptions were the main types.The unsuitable prescriptions were mainly for the inappropriate compatibility of budesonide suspension and compound ipratropium bromide solution, accounting for 23.00%.And the extraordinary prescriptions were mainly for drug prescription without indication, accounting for 49.70%. Conclusion The drug prescription without indication of budesonide suspension in clinic was common.Clinicians should strictly follow the indication of budesonide suspension so as to reduce the economic burden of patients and the incidences of adverse reactions.

关 键 词：布地奈德混悬液 吸入用 处方点评 无适应证用药 用药不适宜 

分 类 号：R974[医药卫生—药品] R725.6[医药卫生—药学]