磷钼杂多酸光度法测定药物中对乙酰氨基酚的含量  

Spectrophotometric Determination of Acetaminophen in Medicine by Phosphomolybdate Heteropoly Acid Spectrophotometry

作　　者：李晓坤 刘涛 Li Xiao-kun;Liu Tao

机构地区：[1]濮阳医学高等专科学校,河南濮阳457000 [2]新乡医学院三全学院,河南新乡453000

出　　处：《化工设计通讯》2019年第11期212-212,214,共2页Chemical Engineering Design Communications

摘　　要：在H2SO4介质中,Mo7O24^6-可以与H2PO4-反应,生成磷钼杂多酸,它能够被对乙酰氨基酚还原成有最大吸收波长(717nm)的磷钼蓝,根据得到磷钼蓝的吸光度,可以间接得到药物中对乙酰氨基酚的含量,因此得到了磷钼杂多酸光度法测定药物中对乙酰氨基酚含量的过程。In H2SO4 medium,Mo7O246-can react with H2PO4-to form phosphorus molybdenum heteropoly acid,which can be reduced by acetaminophen to phosphorus molybdenum blue with maximum absorption wavelength(717nm).According to the absorbance of phosphorus molybdenum blue,The content of acetaminophen in the drug can be obtained indirectly,and thus the process for determining the content of acetaminophen in the drug by the molybdenum heteropoly acid spectrophotometry is obtained.

关 键 词：磷钼杂多酸 对乙酰氨基酚 光度法 

分 类 号：O657.3[理学—分析化学] TQ460.72[理学—化学]