低胆红素与原发性高血压患者左心室肥大相关性分析  

Correlation Analysis between Hypobilirubin and Left Ventricular Hypertrophy in Patients with Essential Hypertension

作　　者：谢燕军 Yanjun XIE(Department of Cardiovascular Medicine,Heshan People's Hospital,Heshan 529700,China)

机构地区：[1]鹤山市人民医院心血管内科

出　　处：《心电图杂志（电子版）》2019年第4期50-51,共2页Journal of Electrocardiogram（Electronic Edition）

摘　　要：目的探讨低胆红素与原发性高血压患者左心室肥大相关性分析。方法选取2017年4月-2019年1月我院收治的原发性高血压患者300例,随机分为对照组、非LVDD组和LVDD组三组,每组100例,对比分析三组患者胆红素以及心脏功能指标的情况。结果三组患者在IVST、LVPW指标对比中,差异无统计学意义(P>0.05);在LVEF、E/A比值的对比中,非LVDD组、LVDD组与对照组相比均明显下降,其差异具有统计学意义(P>0.05);而非LVDD组与LVDD组对比,其相关数值明显下降,差异具有统计学意义(P<0.05);在TBIL、IBIL数值对比中,非LVDD组、LVDD组与对照组的相关数值分析中,有明显有下降的趋势,差异具有统计学意义(P<0.05);而非LVDD组与LVDD组对比中,数值明显下降,其差异具有统计学意义(P<0.05);在DBIL数值对比中,三组患者数据差异无统计学意义(P>0.05)。结论 EH(原发性高血压)病人LVDF和血清胆红素水平有一定的相关性,生理范围内适度升高的胆红素对LVDF(左心室舒张功能)的改善有很大帮助,并对保护心脏起到一定的作用,而LVDD(左心室舒张功能不全)的发生及发展与低TBIL(测定胆红素)、IBIL(间接胆红素)水平有密切的关系。Objective To investigate the correlation between hypobilirubin and left ventricular hypertrophy in patients with essential hypertension. Methods 300 patients with essential hypertension admitted to our hospital from April 2017 to January 2019 were randomly divided into three groups: control group, non-LVDD group and LVDD group, with 100 patients in each group. The bilirubin and cardiac function indicators in the three groups of patients were compared. Results There was no difference in IVST and LVPW between the three groups(P>0.05). In the comparison of LVEF and E/A ratios, the relevant data in the non-LVDD group, LVDD group and control group were significantly decreased, and the difference in values was statistically significant(P>0.05). However, when comparing LVDD group with LVDD group, the relevant values were significantly decreased, and the comparison was statistically significant(P<0.05). In the comparison of TBIL and IBIL values, the values of the non-LVDD group, LVDD group and the control group showed a significant decreasing trend, and the difference was statistically significant(P<0.05). However, in the comparison between the non-LVDD group and LVDD group, the value was significantly decreased, and the difference was statistically significant(P<0.05). In comparison of DBIL values, there was no statistically significant difference among the three groups of patients(P>0.05). Conclusion EH LVDF patients and serum bilirubin level has certain relevance, physiological range of moderately elevated bilirubin on LVDF(left ventricular diastolic function) are of great help to improve, and to protect the heart play a role, and LVDD(left ventricular diastolic dysfunction) in the occurrence and development and low TBIL(determination of bilirubin), IBIL(unconjugated bilirubin) level has a close relationship.

关 键 词：低胆红素 原发性高血压 左心室肥大 分析 

分 类 号：R54[医药卫生—心血管疾病]