2017年院内不同标本来源的大肠埃希菌耐药性分析  

Drug resistance analysis of Escherichia coli isolated from different specimens in 2017

作　　者：赵书平[1] 姜梅杰[1] 陈霞[2] Zhao Shuping;Jiang Meijie;Chen Xia(Department of Clinical Laboratory,Central Hospital of Taian,Taian 271000,China;Department of Emergency,Central Hospital of Taian,Taian 271000,China)

机构地区：[1]泰安市中心医院检验科,271000 [2]泰安市中心医院急诊科,271000

出　　处：《中华临床实验室管理电子杂志》2019年第4期226-229,共4页Chinese Journal of Clinical Laboratory Management(Electronic Edition）

基　　金：山东省自然科学基金(No.ZR2016HL44)

摘　　要：目的及时监测临床分离的主要标本类型和主要科室来源大肠埃希菌的耐药性,为医院抗菌药物及医院感染控制提供依据.方法用WHONET5.6对本院2017年1月1日~12月31日间临床主要标本类型来源的大肠埃希菌(尿液、血液、痰液)和主要科室来源的大肠埃希菌(肾内科病房、ICU病房、儿内科病房)分别进行耐药性分析.结果痰液、血液和尿液标本分离的大肠埃希菌对碳青霉烯类抗菌药物亚胺培南的耐药率分别为1.63%、0.46%和0.30%.对喹诺酮类抗菌药物左氧氟沙星的耐药率分别为45.65%、41.94%和56.70%.ICU病房、肾内科病房和儿内科病房分离的大肠埃希菌对碳青霉烯类抗菌药物亚胺培南的耐药率分别为2.15%、0.00%、0.00%,对喹诺酮类抗菌药物左氧氟沙星的耐药率分别为52.69%、50.00%和21.84%.结论我院主要标本类型和主要科室来源分离的大肠埃希菌对临床常用多数抗菌药物的耐药率相差较大,临床医师及时掌握不同来源主要病原菌的耐药性,可减少治疗失败.Objective To monitor the antimicrobial resistance of Escherichia coli separated from the main specimen types and different ward areas timely,so as to provide basis for the rational use of antimicrobial agents and control of infection.Methods The antimicrobial resistance of non-repeated Escherichia coli strains separated during January 1,2017 to December 31 were analyzed separately by WHONET 5.6 software.These strains were isolated from different specimen and from different wards.Results The resistance rates of Escherichia coli isolated from sputum,blood and urine to imipenem were 1.63%,0.46%and 0.30%,respectively.The resistance rates of levofloxacin to quinolones were 45.65%,41.94%and 56.70%,respectively.The resistance rates of Escherichia coli isolated from ICU,Nephrology and pediatrics wards to imipenem,quinolones and levofloxacin were 2.15%,0.00%,0.00%and 52.69%,50.00%and 21.84%,respectively.Conclusion The resistance rates of Escherichia coli isolated from different specimens and different ward areas in our hospital were significantly different.Timely understanding the resistance of the main pathogens from different sources can reduce treatment failure.

关 键 词：不同科室 不同标本类型 大肠埃希菌 耐药率 

分 类 号：R44[医药卫生—诊断学]