难愈性创面病原菌类型的危险因素分析  

Analysis of the risk factors of pathogenic bacteria type in refractory wound

作　　者：商蓉[1] 倪俊[2] 许献荣[2] Shang Rong;Ni Jun;Xu Xianrong(Department of Infection Control,No.85 Hospital,CPLA,Shanghai 200052,China)

机构地区：[1]解放军第八五医院感染控制科,上海200052 [2]解放军第八五医院烧伤整形外科,上海200052

出　　处：《海军医学杂志》2019年第6期562-564,共3页Journal of Navy Medicine

基　　金：上海市卫生局科研基金(20134489)

摘　　要：目的分析难愈性创面病原菌类型的危险因素,探讨相关防治对策。方法回顾性分析2012年1月至2015年12月解放军第八五医院烧伤整形科医治的138例难愈性创面患者的临床资料,根据创面分泌物病原菌类型将患者分为革兰阳性菌组(83例)和革兰阴性菌组(83例),分析病原菌类型的危险因素。结果创面病原菌中革兰阳性菌占43.77%,革兰阴性菌占56.23%。单因素分析结果显示,年龄、合并基础疾病、低血红蛋白、低白蛋白是难愈性创面革兰阴性菌定植感染的危险因素。多元回归分析结果显示,年龄是难愈性创面革兰阴性菌定植感染的独立危险因素。结论难愈性创面革兰阴性菌占优,年龄大的患者难愈性创面更易感染革兰阴性菌,应针对患者的危险因素采取针对性防治措施。Objective To analyze potential risk factors of pathogenic bacteria type of refractory wound and also to investiage related prevention and treatment countermeasures.Methods Clinical data of refractory wound 138 patients hospitalized from Janurary 2012 to December 2015 in the Burns and Plastic Department were retrospectively analyzed, and the patients were divided into the gram-positive bacteria group and the gram-negative bacteria group in accordance with the pathogenic bacteria type of refractory wound. Then, risk factors of pathogenic bacteria type of refractory wound were analyzed.Results Gram-positive bacteria and gram-negative bacteria accounted for 43.77% and 56.23% respectively. Univariate analysis showed that age, underlying disease, lower hemoglobin and hypoalbuminemia were risk factors of gram-negative bacteria colonization and infection of refractory wound. Multivariate Logistic regression analysis indicated that age was the independent risk factor affecting gram-negative bacteria colonization and infection of refractory wound.Conclusion Gram-negative bacteria are predominant bacteria of refractory wound. Elder patients are more susceptible to gram-negative bacteria colonization and infection of refractory wound. It is necessary to take targeted measures with the detection of risk factors.

关 键 词：创面 难愈性 病原菌 感染 危险因素 

分 类 号：R378[医药卫生—病原生物学]