内蒙古及河北地区2型糖尿病患者勃起功能障碍的患病率  

Prevalence of erectile dysfunction in patients with type 2 diabetes mellitus in Inner Mongolia and Hebei

作　　者：段立志[1] 刘波[2] 张何英 尚国爱[1] 赵海霞 DUAN Lizhi;LIU Bo;ZHANG Heying;SHANG Guoai;ZHAO Haixia(Department of Endocrinology,Port Hospital of Hebei Port Group Co.,Ltd.,Qinhuangdao Hebei 066000;Department of Endocrinology,First Hospital of Qinhuangdao City,Qinhuangdao Hebei 066000;Department of Endocrinology,Inner Mongolia Horqin Youyizhongqi Mongolian Medical Hospital,Ulanhot Inner Mongolia 029400,China)

机构地区：[1]河北港口集团有限公司港口医院内分泌科,河北秦皇岛066000 [2]秦皇岛市第一医院内分泌科,河北秦皇岛066000 [3]内蒙古科尔沁右翼中旗蒙医医院内分泌科,内蒙古乌兰浩特029400

出　　处：《临床与病理杂志》2019年第11期2437-2443,共7页Journal of Clinical and Pathological Research

基　　金：河北省科学技术厅(152777117)~~

摘　　要：目的:比较内蒙古和河北地区2型糖尿病(type 2 diabetes mel litus,T2DM)患者勃起功能障碍(erectile dysfunction,ED)患病率及相关因素,为相关预防工作提供研究依据。方法:选取2015年1月至2017年1月的1360例男性T2DM患者作为研究组,设其中内蒙古自治区医院住院患者510例为A组,河北省医院住院患者850例为B组,选用700名男性体检者作为对照组。对比分析各组的ED患病率。观察研究组年龄、糖尿病病程、BMI、民族、糖化血红蛋白(glycosylated hemoglobin,HbA1c)、尿微量白蛋白与肌酐比值(urinary microalbumin to creatinine ratio,A/C)、胰岛素抵抗指数(insulin resistance index,HOMA-IR)、血清总睾酮水平、颈动脉硬化斑块、下肢动脉硬化斑块、下肢肌电图、合并高血压、合并高脂血症、合并高胆固醇血症等临床特征,对比分析具有不同特征患者的ED患病率。结果:研究组中有346例诊断为ED,患病率为25.44%,对照组中有61例诊断为ED,患病率为8.71%,差异有统计学意义(P<0.05)。A组与B组患者的ED患病率差异无统计学意义(P>0.017),但均高于对照组,差异均有统计学意义(P<0.017)。具有较大年龄,较长糖尿病病程,较高BMI,HbA1c,尿A/C,HOMA-IR水平及民族为汉族的T2DM患者的ED患病率较高,差异均有统计学意义(P<0.05)。Logistic多元回归分析结果显示:T2DM合并ED与年龄,糖尿病病程及BMI,HbA1c,尿A/C,HOMA-IR水平具有相关性(P<0.05)。结论:T2DM患者的ED患病率明显高于血糖正常人群,汉族人群的ED患病率高于蒙古族人群,其患病率与患者的年龄、肥胖程度、血糖控制水平、肾损害程度有关。Objective:To compare the prevalence of erectile dysfunction(ED)between the patients with type 2 diabetes mellitus(T2DM)in the areas of Inner Mongolia and Hebei and its related factors to provide research basis for relevant prevention and intervention work.Methods:A total of 1360 male patients with T2DM from January of 2015 to January of 2017 were selected as a study group,among which 510 hospitalized in Inner Mongolia Autonomous Region were in Group A,850 hospitalized in Hebei Province were in Group B,700 male physical examinees were selected as a control group.The prevalence of ED in each group was compared and analyzed.The age,course of diabetes,BMI,nationality,glycosylated hemoglobin(HbA1c),the urinary microalbumin to creatinine ratio(A/C),the insulin resistance index(HOMA-IR),the serum total testosterone level,the carotid atherosclerosis plaque,the lower extremity atherosclerosis plaque,the lower extremity electromyography,the complication of hypertension,the complication of hyperlipidemia,the complication of hypercholesterolemia of the patients in the study group were observed,and the prevalence of ED in patients with different characteristics were compared and analyzed.Results:In the study group,346 cases were diagnosed as ED,the prevalence was 25.44%,61 cases in the control group were diagnosed as ED,the prevalence was 8.71%,the difference was statistically significant(P<0.05).There was no significant difference of ED prevalence between Group A and Group B(P>0.017),but it was higher than that in the control group(P<0.017).The prevalence of ED was higher in T2DM patients with older age,longer course of diabetes and higher levels of BMI,HbA1c,urinary A/C and HOMA-IR as well as with Han nationality,the differences were statistically significant(P<0.05).Logistic multivariate regression analysis showed that the age,the course of diabetes mellitus and BMI,HbA1c,urinary A/C,HOMA-IR levels were correlated with ED in T2DM(P<0.05).Conclusion:The prevalence of ED in patients with T2DM is significantly higher than tha

关 键 词：2型糖尿病 勃起功能障碍 患病率 相关因素 

分 类 号：R58[医药卫生—内分泌]