中药协定方颗粒剂干预流感样症状的研究  

Study on the effect of traditional Chinese medicine prescription granule on influenza-like symptoms

作　　者：李松 王勇 刘艳 王韦东 刘沁峰 Li Song;Wang Yong;Liu Yan;Wang Weidong;Liu Qinfeng

机构地区：[1]无锡市第二中医医院

出　　处：《中医临床研究》2019年第30期121-123,共3页Clinical Journal Of Chinese Medicine

摘　　要：目的:观察中药协定方颗粒剂治疗流感样病例的疗效,探讨应用优势。方法:取2017年12月-2018年2月在我科就诊的普通流感样病例155例为研究对象,按其接受程度分为中医治疗组85例和西医治疗组70例。中医治疗组给予中药协定方颗粒剂治疗,其中体温<38.5℃给予流感1号方,体温≥38.5℃给予流感2号方;西医治疗组给予西药磷酸奥司他韦口服治疗。对比两组患者3 d内疗效,对比两组患者中体温≥38.5℃患者体温减退时间、咳嗽、咽痛症状改善时间。结果:3 d内疗效方面,中医治疗组总有效率为98.67%,西医治疗组总有效率为87.50%,两组对比差异具有统计学意义(P <0.05)。针对体温≥38.5℃患者,流感2号方在体温减退时间、咽痛以及咳嗽症状改善时间方面明显短于西医治疗组,差异有统计学意义(P <0.01)。两组患者治疗期间均未见明显不良反应。结论中药协定方颗粒剂治疗流感样病例3 d内疗效优于西医治疗组。其中伴有中高度发热患者,中药协定方颗粒剂起效时间明显短于西医治疗组。Objective: To observe the curative effect of Traditional Chinese medicine prescription granule in treating influenzalike cases and to explore its application advantages. Methods: From December 2017 to February 2018, 155 common influenza-like cases admitted to our department were selected as the study subjects. According to their acceptance, 85 cases were divided into the TCM treatment group and 70 cases were divided into the western medicine treatment group. The TCM treatment group was treated with traditional Chinese medicine prescription granule, in which the body temperature < 38.5 ℃ was given formula 1 for influenza and the body temperature ≥ 38.5 ℃ was given formula 2 for influenza. Western medicine treatment group was given oseltamivir phosphate oral treatment. The internal curative effect in 3 d was compared between the two groups of patients, and the hypothermia time, cough and pharyngeal pain symptom improvement time were compared between the two groups of patients with body temperature ≥ 38.5℃. Results: In terms of 3 d internal efficacy, the total effective rate was 98.67% in the TCM treatment group and 87.50% in the western medicine treatment group, and the difference between the two groups was statistically significant(P < 0.05). For patients with body temperature ≥ 38.5 ℃, prescription no. 2 of influenza was significantly shorter than the western treatment group in hypothermia time, pharyngeal pain and cough symptom improvement time(P < 0.01). No obvious adverse reactions were observed during treatment in both groups. Conclusion: The efficacy of traditional Chinese medicine prescription granule in treating influenza-like cases was better than that of western medicine. Among the patients with medium and high fever, the effective time of traditional Chinese medicine prescription granule was significantly shorter than that of western medicine treatment group.

关 键 词：中药协定方颗粒剂 流感 

分 类 号：R283.6[医药卫生—中药学]