我院2017年度药品不良反应报告分析  

Analysis of the 2017 adverse drug reaction report of our hospital

作　　者：杨玉玲[1] YANG YU-LING(The Seventh People’s Hospital of Zhengzhou,Zhengzhou 450016,China)

机构地区：[1]郑州市第七人民医院

出　　处：《首都食品与医药》2019年第22期83-84,共2页Capital Food Medicine

摘　　要：目的对郑州市第七人民医院2017年1~12月药品不良反应(ADR)报告进行分析,为临床安全用药提供参考。方法采用回顾性研究方法,从ADR患者的性别与年龄分布、累及系统和器官分布、给药途径及严重程度等方面对227例药物不良反应报告进行统计分析。结果 227例药物不良反应中,男女比例为1∶1.25,主要发生在30岁以上的患者(76.65%),临床表现主要为皮肤反应(35.1%),给药途径以静脉滴注为主(59.91%);其中严重不良反应33例(14.54%),新的不良反应47例(20.7%)。结论规范临床合理用药意义重大,进一步完善药品安全性再评价,确保临床用药的安全性和有效性。Objective To provide a reference for clinical safety medication,we analyzed the adverse drug reaction(ADR) report of the Seventh People’s Hospital of Zhengzhou from January to December in 2017.Methods Useing a retrospective study,We analyzed 227 adverse drug reactions from the gender and age distribution of ADR patients, system and organ distribution, route of administration, and severity.Results Among the adverse drug reactions, the ratio of male to female was 1:1.25,ADR mainly occurred in patients over 30 years old(76.65%),and the clinical manifestations were mainly skin reactions(35.1%).The main route of administration was intravenous drip(59.91%);Of the 227 adverse drug reactions,33 were serious adverse reactions(14.54%) and 47 were new adverse reactions(20.7%).Conclusion standardizing the rational use of drugs and further improving security reevaluation of drug is necessary to ensure the safety and effectiveness of drugs.

关 键 词：不良反应 分析 合理用药 

分 类 号：R969.3[医药卫生—药理学]