四川省2018年健康人群乙型肝炎表面抗体水平调查  

Hepatitis B surface antibody levels among healthy people in Sichuan province, 2018

作　　者：杨庆 陈筱纯[1] 童文彬[1] 刘宇[1] 包莹 漆琪[1] Yang Qing;Chen Xiaochun;Tong Wenbin;Liu Yu;Bao Ying;Qi Qi(Sichuan Provincial Center for Disease Control and Prevention,Chengdu 610041,Sichuan,China)

机构地区：[1]四川省疾病预防控制中心

出　　处：《中国疫苗和免疫》2019年第5期524-527,共4页Chinese Journal of Vaccines and Immunization

摘　　要：目的评价四川省2018年健康人群乙型肝炎(乙肝)表面抗体(Hepatitis B virus surface antibody,HBsAb)水平。方法采用分层随机抽样方法,在四川省9个县区随机抽取7个年龄组的健康人群,采用酶联免疫吸附试验检测血清HBsAb,分析HBsAb阳性率。结果调查人群HBsAb总阳性率为69.33%(1318/1901);9个监测地区阳性率在60.75%-82.38%之间(χ^2=38.52,P<0.01);各年龄组阳性率在46.58%(7-14岁组)-98.05%(<1岁组)之间(χ^2=247.58,P<0.01)。在1-14岁人群中,有、无或不详乙肝疫苗(HepB)免疫史人群的HBsAb阳性率分别为65.93%、47.50%(x2=15.79,P<0.01)。结论四川省2018年健康人群HBsAb总阳性率较高,需加强薄弱地区或重点人群的HepB接种工作。Objective To assess hepatitis B surface antibody(HBsAb)levels among healthy people in Sichuan province in 2018.Methods We used a stratified random sampling technique to select healthy individuals from 9 districts of Sichuan into 7 age-group strata.We tested sera for HBsAb using enzyme-linked immunosorbent assays for an analysis of HBsAb positivity rates.Results The overall positivity rate of HBsAb was 69.33%(1318/1901),with regionspecific positivity rates ranging from 60.75%to 82.38%(χ^ 2=38.52,P<0.01),and age-specific positivity rates ranging from 46.58%(7-14 years old)to 98.05%(<1 year old)(χ^ 2=247.58,P<0.01).Among 1-14-year-old children,the HBsAb positivity rate was 65.93%for those who had received hepatitis B vaccine(HepB),and 47.50%for those who had not received HepB(χ^ 2=15.79,P<0.01).Conclusion The overall positivity rate of HBsAb was high among healthy people in Sichuan in 2018.We should strengthen HepB vaccination in vulnerable areas and for priority populations.

关 键 词：乙型肝炎 乙型肝炎表面抗体 健康人群 

分 类 号：R186[医药卫生—流行病学]