用于测量J偶合常数的同时多层选择性恒时J分解谱的方法（英文）  

Simultaneous Multi-Slice Selective Constant-Time J-Resolved Spectroscopy for Measuring J Values

作　　者：陈金永 曾庆[1] 林雁勤[1,2] 陈忠 CHEN Jin-yong;ZENG Qing;LIN Yan-qin;CHEN Zhong(Department of Electronic Science,Fujian Provincial Key Laboratory of Plasma and Magnetic Resonance,State Key Laboratory of Physical Chemistry and Solid Surfaces,Xiamen University,Xiamen 361005,China;Shenzhen Research Institute of Xiamen University,Shenzhen 518057,China)

机构地区：[1]厦门大学电子科学系,福建省等离子体与磁共振研究重点实验室,固体表面物理化学国家重点实验室,福建厦门361005 [2]厦门大学深圳研究院,广东深圳518057

出　　处：《波谱学杂志》2019年第4期456-462,共7页Chinese Journal of Magnetic Resonance

基　　金：the National Natural Science Foundation of China(U1732158 and U1632274);the Key Science and Technique Project of Fujian Province(2018Y0077);the Natural Science Foundation of Guangdong Province(2018A030313794);the Fundamental Research Funds for the Central Universities(20720170036)

摘　　要：标量偶合是核磁共振(NMR)波谱的一个重要参数.其中氢-氢偶合能提供关于分子结构的有用信息.但是,在复杂的偶合网络中解析出氢-氢偶合常数(JH-H)较为困难.本文提出了一种基于空间编码选择性恒时演化的测量JH-H的方法,利用一次实验就能解析分子中所有氢核的偶合网络,并测量JH-H.该方法被称为同时多层选择性恒时J分解谱(SMS-SECTJRES).它结合空间编码梯度和选择性恒时演化,并利用平面回波谱成像(EPSI)采样模块,从不同的空间位置提取出对应不同氢核偶合网络的J分解谱,促进了NMR技术在分子结构解析中的进一步应用.Scalar coupling is an important parameter in nuclear magnetic resonance(NMR).The proton-proton coupling constant JH-H provides valuable information on molecular structure.However,determining JH-H value in complex coupling networks is still challenging.Here,we propose a method called simultaneous multi-slice selective constant-time J-resolved spectroscopy(SMS-SECTJRES)to measure JH-H values of all coupling networks of a molecule simultaneously in one experiment.In this method,gradient-encoded selective refocusing is used during a fixed evolution time,combined with echo planar spectroscopic imaging(EPSI)detection module to extract different selective J-edited spectra in different spatial positions.This new method is conducive to reveal coupling networks and the analysis of molecular structures.

关 键 词：核磁共振 标量偶合 选择性恒时 平面回波谱成像 分子结构解析 

分 类 号：O482.53[理学—固体物理]