多囊卵巢综合征性不孕患者采用不同促排卵方案的临床效果  

Clinical effects of different ovulation induction schemes in infertile women with polycystic ovary syndrome

作　　者：倪金莲[1] 彭璇[1] NI Jin-Lian;PENG Xuan(Department of Assisted Reproduction,Jiujiang Municipal Maternal and Child Health Care Hospital,Jiujiang,Jiangxi 332000,China)

机构地区：[1]九江市妇幼保健院辅助生殖科

出　　处：《中国妇幼保健》2019年第22期5252-5254,共3页Maternal and Child Health Care of China

基　　金：江西省卫生计生委科技计划项目(赣卫科教字〔2017〕18号)

摘　　要：目的 探讨多囊卵巢综合征(PCOS)性不孕患者采用不同促排卵方案的临床效果。方法 收集2014年1月-2017年12月九江市妇幼保健院83例PCOS性不孕患者临床资料,根据促排卵方案将患者分为来曲唑组(A组)、来曲唑+尿促性素组(B组)、来曲唑+尿促卵泡素组(C组)。比较3组促排卵效果及妊娠结局。结果 3组优势卵泡个数、单卵泡发育率、临床妊娠率及流产率比较差异均有统计学意义(均P<0. 05)。3组排卵率、卵巢过度刺激综合征(OHSS)发生率、异位妊娠率及多胎妊娠率比较差异均无统计学意义(均P>0. 05)。结论 联合促排卵方案治疗PCOS性不孕患者简单、有效、安全,可提高临床妊娠率,降低流产率。Objective To explore the clinical effects of different ovulation induction schemes in infertile women with polycystic ovary syndrome(PCOS).Methods The clinical data of 83 infertile women with PCOS were collected from Jiujiang Municipal Maternal and Child Health Care Hospital from January 2014 to December 2017,then the patients were divided into letrozole group(A group),letrozole+menotrophin group(B group),and letrozole+urofollitropin group(C group).The ovulation induction effects and pregnancy outcomes in the three groups were compared.Results There were statistically significant differences in the number of dominant follicles,single follicle development rate,clinical pregnancy rate,and abortion rate among the three groups(P<0.05).There was no statistically significant difference in ovulation rate,incidence rate of ovarian hyperstimulation syndrome(OHSS),and multiple pregnancy rate among the three groups(P>0.05).Conclusion Combined ovulation induction scheme is simple,effective,and safe in treatment of infertile women with PCOS,which can improve clinical pregnancy rate and reduce abortion rate.

关 键 词：多囊卵巢综合征 不孕 促排卵 

分 类 号：R321.2[医药卫生—人体解剖和组织胚胎学]