临床药师参与治疗1例人工膝关节置换术后迟发感染的药学实践  

Pharmaceutical Practice of Clinical Pharmacists Participating in Late-onset Infection after Artificial Knee Joints Replacement

作　　者：解沛涛 董利森[1] 苏长海[1] 刘柯欣 Xie Peitao;Dong Lisen;Su Changhai;Liu Kexin(Department of Pharmacy,Erdos Central Hospital,Inner Mongolia Ordos 017000,China;Ulanmulun Town Bulian Health Center in Ordos)

机构地区：[1]鄂尔多斯市中心医院药剂科,内蒙古鄂尔多斯017000 [2]鄂尔多斯市乌兰木伦镇布连卫生院

出　　处：《中国药师》2019年第11期2058-2061,共4页China Pharmacist

摘　　要：人工膝关节置换术后迟发感染的保守治疗成功率低,需重新关节置换联合长疗程抗菌药物治疗。临床药师通过日常查房,对1例人工膝关节置换术2年后发生人工膝关节周围感染的患者进行监护,结合相关文献报道,从药物选择和剂量调整方面向医师提出用药建议,参与制定患者药物治疗方案及方案调整,减少了药品不良反应的发生,保证患者的用药安全。最终在未行关节重新置换情况下协助医师保守治疗成功,体现了临床药师参与人工关节感染治疗中价值,对于提高临床抗感染合理用药具有重要意义。The success rate of conservative treatment for delayed infection after total knee arthroplasty is low,and combination with long-term antibiotic therapy is necessary.Clinical pharmacists performed ward round and pharmaceutical care for one patient with infection around the artificial joints after total knee joints replacement two years ago.According to the relevant literatures,clinical pharmacist provided medical advice for physician from drug choice and dosage adjustment,and participated in the medicine therapeutic scheme adjustment for the patient,which reduced the occurrence of adverse drug reactions and ensured the patient’s medication safety.The success of conservative treatment without joint replacement reflects the participation value of clinical pharmacists in the treatment of artificial joint infections,which is of great significance to improve the rational use of anti-infection drugs in clinical practice.

关 键 词：人工膝关节迟发感染 路登葡萄球菌 利福平 利奈唑胺 

分 类 号：R97[医药卫生—药品]