ICP-OES法测定砂烫前后骨碎补中10种微量元素含量  

Determination of Ten Trace Elements in Drynariae Rhizoma before and after Stir-baked with Sand by ICPOES

作　　者：马杰 彭玲娜 李瑞莲 王湘波 Ma Jie;Peng Lingna;Li Ruilian;Wang Xiangbo(Hunan Institute for Drug Control,Changsha 410001,China;Hunan Engineering&Technology Research Center for Pharmaceutical Quality Evaluation)

机构地区：[1]湖南省药品检验研究院,长沙410001 [2]湖南省药品质量评价工程技术中心

出　　处：《中国药师》2019年第11期2094-2097,共4页China Pharmacist

基　　金：国家药典委员会药品标准制修订研究项目(编号:2018Z006)

摘　　要：目的:采用电感耦合等离子体发射光谱(ICP-OES)测定骨碎补药材及烫骨碎补中10种微量元素(Al、Ca、Cd、Cr、Cu、Fe、Mg、Ni、Pb、Zn)的含量并分析。方法:将骨碎补药材及对应的烫骨碎补饮片粉末经微波消解后,采用ICP-OES法测定。结果:烫制后Al、Pb的含量明显降低,且多种元素间呈现出一定的相关性。所有元素的的线性相关系数为0.9978~1.0000,检出限为0.003~0.141 mg·kg^-1,重复性试验RSD为0.1%~2.8%,回收率为93.5%~103.1%。结论:建立的方法简便、准确,可用于同时测定骨碎补中10种微量元素的含量。Objective:To determine and analyze ten trace elements(Al,Ca,Cd,Cr,Cu,Fe,Mg,Ni,Pb,Zn)in Drynariae Rhizoma and their preparations stir-baked with sand by inductively coupled plasma-emission spectrometry(ICP-OES).Methods:The powders of Drynariae Rhizoma and their preparations stir-baked with sand were digested by microwave and determined by ICP-OES.Results:The contents of Al and Pb decreased obviously after stir-baked with sand,and there was a certain correlation among the elements.The linear correlation coefficients of all elements were 0.9978-1.0000,the detection limits were 0.003-0.141 mg·kg^-1,the RSDs of repeatability test were 0.1%-2.8%,and the recoveries were 93.5%-103.1%.Conclusion:The method is simple and accurate,which can be used to simultaneously determine the contents of ten trace elements in Drynariae Rhizoma.

关 键 词：电感耦合等离子体发射光谱法 含量测定 骨碎补 砂烫法 微量元素 

分 类 号：R927.1[医药卫生—药学]