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作 者:王蓉 孔丹丹[2] 杨世海 杨美华[2] WANG Rong;KONG Dan-dan;YANG Shi-hai;YANG Mei-hua(College of Traditional Chinese Medicine,Jilin Agricultural University,Changchun 130118;Institute of Medicinal Plant Development,Chinese Academy of Medical Sciences,Peking Union Medical College,Beijing 100193)
机构地区:[1]吉林农业大学中药材学院,长春130118 [2]中国医学科学院,北京协和医学院药用植物研究所,北京100193
出 处:《分析试验室》2019年第11期1366-1373,共8页Chinese Journal of Analysis Laboratory
基 金:中国医学科学院医学与健康科技创新工程(2017-I2M-1-013);协和青年基金资助;中央高校基本科研业务费专项资金(3332018201)资助
摘 要:电化学生物传感器因具有较高的选择性与灵敏度,较低的成本与易于携带等优点,已被广泛应用于各大领域中重金属的实时监测。介绍了4类电化学生物传感器在生态环境、食品安全、医药及临床样本等方面的应用情况,以期对电化学生物传感器的未来发展方向提供一定的理论依据。Electrochemical biosensor is a kind of fast screening integrated device which combined the powerful analytical function of electrochemistry with the specific identification feature of biological components.The immobilized bio-molecules or biosomes were employed as the sensing elements,and the functional electrodes were utilized as the transducer.By detecting the changes of electrochemical signal produced by the interaction of target metal ions with the sensing elements,the rapid determination was achieved.Due to the high selectivity,sensitivity,low cost and portability of electrochemical biosensor,it has been widely used for real time and fast screening analysis of heavy metals in the fields of environment monitoring,food safety,biomedicine and clinical fields.In this review,the electrochemical biosensors were briefly introduced from definition,test principle and category.Besides,in order to provide some theory for the future development,four main types of electrochemical biosensors and the applications in ecological environment,food safety,medicine and clinical samples were emphatically discussed.
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