抗生素联合糖皮质激素治疗老年慢性阻塞性肺病急性发作期的临床效果观察  

Clinical Observation of Antibiotic Combined with Glucocorticoid in the Treatment of Acute Exacerbation of Chronic Obstructive Pulmonary Disease in the Elderly

作　　者：丁春晖[1] DING Chun-hui(Department of Internal Medicine,Taixing Hospital of Traditional Chinese Medicine,Taixing,Jiangsu Province,225400 China)

机构地区：[1]泰兴市中医院内科

出　　处：《系统医学》2019年第21期91-93,共3页Systems Medicine

摘　　要：目的探讨抗生素联合糖皮质激素治疗老年慢性阻塞性肺病急性发作期的临床效果。方法将该院2016年1月—2019年1月期间收治的60例老年慢性阻塞性肺病患者随机分为两组,在常规平喘止咳化痰基础上,对照组患者接受抗生素抗感染治疗,观察组在对照组的基础上加用糖皮质激素,通过对比两组患者治疗有效率、及临床不良反应情况之间的差异,继而探究抗生素联合糖皮质激素治疗老年慢性阻塞性肺病的临床可行性与应用价值。结果观察组患者总有效率(96.67%)显著高于对照组(83.33%)(χ^2=7.651,P=0.005),观察组不良反应率(13.33%)低于对照组(26.67%),差异有统计学意义(χ^2=18.628,P=0.001)。结论抗生素联合糖皮质激素治疗老年慢性阻塞性肺病急性发作期的疗效显著,能够在有效改善患者气急,降低不良反应发生率,缩短住院时程,安全性高,值得推广。Objective To investigate the clinical effects of antibiotics combined with glucocorticoids in the treatment of acute exacerbation of chronic obstructive pulmonary disease in the elderly.Methods Sixty elderly patients with chronic obstructive pulmonary disease admitted to the hospital from January 2016 to January 2019 were randomly divided into two groups.On the basis of routine asthma,cough and phlegm,the control group received antibiotic anti-infective treatment.The observation group added glucocorticoids to the control group.By comparing the difference between treatment efficiency and clinical adverse reactions,the clinical feasibility of antibiotics combined with glucocorticoids in the treatment of elderly patients with chronic obstructive pulmonary disease was explored.Results The total effective rate(96.67%)of the observation group was significantly higher than that of the control group(83.33%),the difference was statistically significant(χ^2=7.651,P=0.005).The adverse reaction rate of the observation group(13.33%)was lower than that of the control group(26.67%).The difference was statistically significante(χ^2=18.628,P=0.001).Conclusion Antibiotic combined with glucocorticoid is effective in the treatment of acute exacerbation of chronic obstructive pulmonary disease in the elderly.It can effectively improve the patient's shortness of breath,reduce the incidence of adverse reactions,shorten the hospitalization time,and has high safety.It is worth promoting.

关 键 词：抗生素 糖皮质激素 老年慢性阻塞性肺病 不良反应 

分 类 号：R563.9[医药卫生—呼吸系统]