甲氨蝶呤与子宫动脉栓塞联合治疗疤痕妊娠临床分析  

Clinical Analysis of Methotrexate Combined with Uterine Artery Embolization in the Treatment of Scar Pregnancy

作　　者：姚晓芳[1] YAO Xiao-fang(Department of Obstetrics and Gynecology,Xinghua Hospital of Traditional Chinese Medicine,Xinghua,Jiangsu Province,225700 China)

机构地区：[1]江苏省兴化市中医院妇产科

出　　处：《中外医疗》2019年第31期73-75,共3页China & Foreign Medical Treatment

摘　　要：目的分析疤痕妊娠患者接受甲氨蝶呤联合子宫动脉栓塞治疗的临床应用价值。方法该次方便选择2017年1月-2019年2月该院收治的60例疤痕妊娠患者为研究对象,参照计算机随机抽选结果分为观察组与对照组,对照组患者单纯接受甲氨蝶呤注射治疗,观察组患者接受甲氨蝶呤注射联合子宫动脉栓塞治疗,治疗后两组患者均接受清宫术,比较治疗效果,统计并分析各组患者临床相关指标差异。计算各组不良反应发生率。结果观察组患者治疗总有效率明显高于对照组(P<0.05),同时,观察组患者术中出血量(104.39±11.23)m L少于对照组,阴道流血时间(5.33±1.02)d、包块完全消失时间(16.44±2.01)d、HCG恢复正常时间(19.38±1.01)h、住院总时间(8.03±1.12)d均明显短于对照组(t=30.48、15.49、26.36、18.09、20.38,P<0.05)。观察组患者术后发生不良反应的概率较对照组相比更低(P<0.05)。结论疤痕妊娠患者接受甲氨蝶呤联合子宫动脉栓塞治疗效果更佳,能够减少出血量,加速患者康复,预防不良反应,值得临床应用与推广。Objective To analyze the clinical value of methotrexate combined with uterine artery embolization in patients with scar pregnancy. Methods Sixty patients with scar pregnancy admitted to the hospital from January 2017 to February2019 were Conveniently selected as the study subjects. The results of computer sampling were divided into observation group and control group. The control group received methotrexate injection alone. Patients in the observation group received methotrexate injection combined with uterine artery embolization. After treatment, both groups received uterine curettage,and the treatment effects were compared. The clinically relevant indicators of each group were statistically analyzed. The incidence of adverse reactions in each group was calculated. Results The total effective rate of the observation group was significantly higher than that of the control group(P<0.05). At the same time, the intraoperative blood loss(104.39±11.23) m L was lower in the observation group than in the control group, and the vaginal bleeding time(5.33±1.02) d. The complete disappearance time of the block(16.44±2.01) d, the normal time of HCG recovery(19.38±1.01)h, and the total hospitalization time(8.03±1.12) d were significantly shorter than the control group(t=30.480, 15.490, 26.360, 18.090, 20.380, P<0.05). The probability of adverse reactions in the observation group was lower than that in the control group(P<0.05). Conclusion Patients with scar pregnancy have better treatment with methotrexate combined with uterine artery embolization, which can reduce the amount of bleeding, accelerate the recovery of patients and prevent adverse reactions. It is worthy of clinical application and promotion.

关 键 词：甲氨蝶呤 子宫动脉栓塞 疤痕妊娠 临床分析 

分 类 号：R71[医药卫生—妇产科学]