乌司他丁治疗创伤失血性休克后多器官功能衰竭的效果  

Effect of Ulinastatin on Multiple Organ Failure after Traumatic Hemorrhagic Shock

作　　者：徐建安 李王安[1] Xu Jian’an(Emergency department of Huizhou first people’s Hospital,Huizhou Guangdong 516000)

机构地区：[1]惠州市第一人民医院急诊科

出　　处：《黑龙江医药》2019年第6期1267-1269,共3页Heilongjiang Medicine journal

基　　金：惠州市科技局课题项目(项目编号:2016Y058);项目名称:依托智慧医疗平台构建院前院内严重创伤一体化急救模式

摘　　要：目的:探讨在创伤失血性休克后胃肠功能障碍合并多器官功能衰竭综合征患者治疗中,采取乌司他丁的临床应用效果。方法:选取我院接诊的创伤失血性休克后胃肠功能障碍合并多器官功能衰竭综合征患者54例,随机分为对照组与观察组,各组27例,分别采取常规治疗与乌司他丁治疗,观察两组患者治疗前与治疗3天后胃肠功能评分、急性生理学与慢性健康状况(APACHEⅡ)评分。结果:观察组治疗3天后胃肠功能评分、APACHEⅡ评分均明显低于对照组(P<0.05)。结论:在创伤失血性休克后胃肠功能障碍合并多器官功能衰竭综合征治疗中,采用乌司他丁可帮助患者快速恢复胃肠功能,减轻疾病严重程度,值得推广。Objective: To explore the clinical effect of ulinastatin in the treatment of gastrointestinal dysfunction with multiple organ failure syndrome after traumatic hemorrhagic shock.Methods: 54 patients with gastrointestinal dysfunction and multiple organ failure syndrome after traumatic hemorrhagic shock were randomly divided into control group and observation group.27 patients in each group were treated with routine therapy and ulinastatin respectively.Gastrointestinal function score,acute physiology and chronic health status(APACHE Ⅱ) score were observed before and after treatment.Results: The gastrointestinal function score and Apache Ⅱscore in the observation group were significantly lower than those in the control group(P< 0.05).Conclusion: In the treatment of gastrointestinal dysfunction combined with multiple organ failure syndrome after traumatic hemorrhagic shock,ulinastatin can help patients recover gastrointestinal function quickly and reduce the severity of the disease,which is worth popularizing.

关 键 词：乌司他丁 创伤失血性休克 多器官功能衰竭综合征 

分 类 号：R441.9[医药卫生—诊断学]