纹带棒状杆菌感染的患者临床科室、标本分布特点与易患因素分析  

Distribution characteristics and predisposing factors of Corynebacterium striatum infection

作　　者：曾丽娟 胡辛兰[1,3] 林风辉[1,2] 陈东杰[1,3] 薛贻敏[1,2] 陈茜[1,2] 陈明光[1,2] 陈虹[1,2] 程坤 杨超 ZENG Li-juan;HU Xin-lan;LIN Feng-hui;CHEN Dong-jie;XUE Yi-min;CHEN Qian;CHEN Ming-guang;CHEN Hong;CHENG Kun;YANG Chao(Shengli Clinical Medical College,Fujian Medical University,Fuzhou 350001,China;Cardiac Intensive Care Unit,Fujian Provincial Hospital,Fuzhou 350001,China;Larboratory,Fujian Provincial Hospital,Fuzhou 350001,China)

机构地区：[1]福建医科大学省立临床医学院,福州350001 [2]福建省立医院重症医学四科,福州350001 [3]福建省立医院检验科,福州350001

出　　处：《创伤与急诊电子杂志》2019年第3期127-129,151,共4页Journal of Trauma and Emergency(Electronic Version)

基　　金：福建省医学创新课题(2016-CX-1);福建省重症医学中心建设项目(2017-510)

摘　　要：目的为临床预防及治疗纹带棒状杆菌作出指导。方法回顾性分析本院2017年9月至2019年6月检出纹带棒状杆菌的114例患者资料,分析该菌的临床科室分布、标本分布特点,并对其易患因素进行统计。结果114例纹带棒状杆菌感染患者中97.4%患者存在入住ICU、以前使用广谱抗生素、机械通气或植入侵入性导管等易患因素,88.6%患者有脑卒中后遗症、恶性肿瘤、慢性阻塞性肺疾病或糖尿病等基础疾病。下呼吸道标本检出率最高,ICU中患者检出率最高,分别为57.9%和29.8%。结论纹带棒状杆菌感染多发生于有各种基础疾病的患者,各种易患因素又促成该菌感染,应积极治疗原发病,合理应用抗生素,减少侵入性导管的植入,严格执行消毒隔离措施,以防止纹带棒状杆菌的院内感染和传播,并采取及时、适当的治疗。Objective To provide guidance for the clinical prevention and treatment of Corynebacterium striatum.Methods A retrospective observational study was conducted on the data from September 2017 to June 2019 about 114 cases of Corynebacterium striatum detected in the Laboratory Department of Fujian Provincial Hospital.The clinical distribution characteristics of the bacteria were analyzed and the predisposing factors were discussed.Results Among 114 cases of Corynebacterium striatum infection,97.4% had predisposing factors such as ICU admission,previous use of broad-spectrum antibiotics,mechanical ventilation or implantation of invasive catheters,88.6% had underlying diseases such as stroke sequelae,malignant tumors,chronic obstructive pulmonary disease or diabetes.The detection rate of Corynebacterium striatum in lower respiratory tract specimens and the specimens from patients admitted to ICU were 57.9% and 29.8%respectively,both of which were the highest in its group.Conclusion Corynebacterium striatum infection mostly occurs in patients with various underlying diseases,and various predisposing factors contribute to the occurrence of the disease.We should actively treat the primary diseases,rationally use antibiotics,reduce the implantation of invasive catheters,strictly implement disinfection and isolation measures to prevent nosocomial infection and transmission of Corynebacterium striatum,and take timely and appropriate treatment.

关 键 词：纹带棒状杆菌 分布特点 易患因素 

分 类 号：R47[医药卫生—护理学]