轮状病毒腹泻流行病学特征分析  

The analysis of epidemiological characteristics of rotavirus diarrhea clinical value

作　　者：丁小兰[1] 刘春霞[1] 贾建美[1] 崔蕾[2] DING Xiaolan;LIU Chunxia;JIA Jianmei;CUI Lei(Department of Clinical Laboratory,the Nantong Rich Hospital,Nantong,Jiangsu 226010,China;Department of Pediatrics,Haian County People's Hospital of Nantong,Nantong,Jiangsu 226600,China)

机构地区：[1]南通瑞慈医院检验科,江苏南通226010 [2]南通市海安县人民医院儿科,江苏南通226600

出　　处：《检验医学与临床》2019年第S02期1-4,共4页Laboratory Medicine and Clinic

基　　金：江苏省南通市科技计划项目临床医学科技专项(HS149111)。

摘　　要：目的探讨分析患儿粪便轮状病毒腹泻流行病学特征分析,为儿童轮状病毒感染的诊断治疗提供参考依据。方法选取2016年10月至2017年9月该院收治的65例腹泻患儿,收集粪便常规检测,并联合使用胶体金免疫层析法进行A群轮状病毒抗原检测,观察对比不同年龄阶段、不同季节以及不同粪便形态的患儿A群轮状病毒阳性检出率。结果送检的65例患儿粪便标本中检出20例阳性,总体阳性率为30.8%;6个月至<2岁患儿的阳性检出率高于<6个月和2~<6岁的患儿,差异有统计学意义(P<0.05);秋冬季节患儿的RV阳性检出率高于春夏季节,差异有统计学意义(P<0.05);患儿的蛋花汤样便中的RV阳性检出率高于水样便和黏液便,差异有统计学意义(P<0.05)。结论儿童腹泻大多是由A群轮状病毒的感染引起的,分析轮状病毒引起腹泻的流行病学特征,对于临床上小儿腹泻的诊断、治疗提供了准确、可信的参考依据。Objective To analyze the results of routine detection of rotavirus antigen in group A of feces and its clinical value,and to provide a reference for the diagnosis and treatment of rotavirus infection in children.Methods Sixty-five children with diarrhea admitted to the hospital from Oct.2016 to Sept.2017 were enrolled in this study.Stool samples were collected routinely and combined with colloidal gold immunochromatography for the detection of group A rotavirus antigen.The observation was compared with different age groups A group of rotavirus positive detection rate in children with different stool patterns and seasons,the results were recorded at any time and analyzed its clinical value.Results Totally 20 cases were detected in stool samples of 65 cases,the overall positive rate was 30.8%.The positive rate of children in 6 months^2 years old was significantly higher than that in children<6 months and 2~6 years old,the difference was statistically significant(P<0.05).The positive rate of RV positive in autumn and winter was higher than that in spring and summer,the difference was statistically significant(P<0.05).The positive rate of RV in egg drop soup was higher than that in watery and mucus,the difference was statistically significant(P<0.05).Conclusion Most children′s diarrhea is caused by group A rotavirus infection.The detection results of rotavirus antigen provide an accurate and credible reference basis for the diagnosis and treatment of clinical pediatric diarrhea.

关 键 词：小儿腹泻 A群轮状病毒 抗原检测 

分 类 号：R72[医药卫生—儿科]