有机紫外线吸收剂二苯甲酮-3的环境污染及其内分泌干扰作用研究进展  

Research progress in environmental pollution and endocrine disruption of the UV filter benzophenone-3

作　　者：卢婍 周义军[1] 田英[1,2] LU Qi;ZHOU Yi-jun;TIAN Ying(Shanghai Jiao Tong University School of Public Health,Shanghai 200025,China;MOE and Shanghai Key Laboratory of Children's Environmental Health,Xinhua Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200092,China)

机构地区：[1]上海交通大学公共卫生学院,上海200025 [2]上海交通大学医学院附属新华医院环境与儿童健康重点实验室,上海200092

出　　处：《上海交通大学学报（医学版）》2019年第11期1320-1324,共5页Journal of Shanghai Jiao tong University:Medical Science

基　　金：国家重点研发计划(2017YFC1600500)~~

摘　　要：二苯甲酮-3是目前使用最广泛的苯甲酮型紫外线吸收剂,具有亲脂性、光稳定性和生物累积性。二苯甲酮-3在环境水体中广泛存在,并且可在人体内被检出,其潜在毒性(特别是内分泌干扰作用)已经引起了人们的关注。在国外文献中可以获得较多二苯甲酮-3在环境和人体中暴露的有关数据,但我国相关方面的研究较少。鉴于二苯甲酮-3的广泛存在及其内分泌干扰作用,未来研究应着重关注其对人群包括内分泌干扰作用在内的潜在毒性及其机制探究。Benzophenone-3 is the most widely used benzophenone type UV filter,which is lipophilic,light stable and bioaccumulative.Benzophenone-3 is widely present in environmental waters and can be detected in humans.Its potential toxicity(especially endocrine disruption)has attracted people's attention.There are a lot of related data on the exposure of benzophenone-3 in the environment and humans from foreign literatures,but there are few studies on related aspects in China.In the view of widespread presence of benzophenone-3 and its endocrine disruption,future researches should focus on its potential toxicity to the population including endocrine disruption and the mechanisms.

关 键 词：二苯甲酮-3 环境暴露 人体暴露 内分泌干扰作用 

分 类 号：R12[医药卫生—环境卫生学]