头穴针刺结合尼莫地平治疗脑卒中后轻度认知功能障碍的临床研究  

Clinical Effect of Scalp Acupuncture combined with Nimodipine on MMSE,HDS-R and BI Scores in the Treatment of Vascular Cognitive Impairment with No Dementia

作　　者：李兰辰 金晓宇 曾学清[1] LI Lan-chen;JIN Xiao-yu;ZENG Xue-qing(General Hospital of Daqing Oil Field,Daqing Heilongjiang 163001,China)

机构地区：[1]大庆油田总医院

出　　处：《中医药导报》2019年第22期49-52,共4页Guiding Journal of Traditional Chinese Medicine and Pharmacy

基　　金：黑龙江省自然科学基金项目(D201641)

摘　　要：目的:观察头穴针刺结合尼莫地平治疗脑卒中后轻度认知功能障碍(vascular cognitive impairment with no dementia,VCIND)的临床疗效及对患者MMSE、HDS-R与BI评分的影响。方法:将68例脑卒中后轻度认知功能障碍患者随机分为对照组与治疗组各34例,对照组患者采用尼莫地平治疗,治疗组患者采用头穴针刺结合尼莫地平治疗。观察并比较两组患者的中医证侯积分(记忆、面色、舌质、脉象),MMSE、HDS-R与BI评分,临床疗效以及不良反应发生情况。结果:治疗组患者总有效率(97.05%)显著高于对照组(79.41%)(P<0.05);治疗后两组患者记忆、面色、舌质、脉象等中医证候积分均降低,且治疗组中医证候积分低于对照组(P<0.05);治疗后两组患者MMSE、HDS-R评分均降低,BI评分升高,且治疗组患者MMSE、HDS-R评分均低于对照组(P<0.05),BI评分高于对照组(P<0.05);对照组不良反应发生率(17.65%)高于治疗组(5.88%),但差异无统计学意义(P>0.05)。结论:头穴针刺结合尼莫地平治疗VCIND,能有效缓解患者的症状,改善脑卒中后认知障碍,提高临床疗效。Objective:To investigate the clinical effect of scalp acupuncture combined with nimodipine on MMSE,HDS-R and BI scores in the treatment of vascular cognitive impairment with no dementia(VCIND).Methods:68 cases of VCIND were divided into two groups according to the random number table method,each with 34 cases.The control group received the nimodipine,while the study group received the scalp acupuncture combined with nimodipine.Then the scores of symptom(memory,complexion,tongue,pulse),MMSE,HDS-R and BI,along with clinical efficacy and adverse reactions were compared between groups.Results:The total effective rate of the study group was significantly higher than that of the control group(97.05%vs 79.41%)(P<0.05).After treatment,the scores of memory,complexion,tongue quality and pulse condition of the two groups were decreased,which were lower in the study group than in the control group after treatment(P<0.05).After treatment,the scores of MMSE and HDS-R in both two groups decreased,while BI scores increased,the study group had lower scores of MMSE and HDS-R as well as higher BI score than those of the control group(P<0.05).The incidence of adverse reactions in the control group(17.65%)was higher than that in the study group(5.88%),but the difference was not statistically significant(P>0.05).Conclusion:The application of scalp acupuncture combined with nimodipine can effectively alleviate the symptom scores and cognitive impairment for VCIND patients.

关 键 词：脑卒中后轻度认知功能障碍 头穴针刺 尼莫地平 MMSE评分 HDS-R评分 BI评分 

分 类 号：R246.6[医药卫生—针灸推拿学]