辐照血液在血液学方面的临床应用  

Clinical Application of Blood Product Irradiation for Hematological Purpose——Review

作　　者：曹庆盛 王明慧[1] CAO Qing-Sheng;WANG Ming-Hui(Department of Blood Component,Beijing Red Cross Blood Service Center,Beijing 100088,China)

机构地区：[1]北京市红十字血液中心成分科

出　　处：《中国实验血液学杂志》2019年第6期2030-2034,共5页Journal of Experimental Hematology

摘　　要：随着输血医学的发展和对输血诊疗技术的掌握,我国辐照血液制品的应用在逐步的增加。近年来,患者输注射线辐照过的血液的比例日益增高,国外有些国家输注射线辐照过的血液应用率高达95%,而目前在国内还处于推广阶段。本文总结了常用的血液辐照方法,包括辐照源的选择,核心剂量和常见辐照对象,比较了不同辐照方法的差异,并对血液辐照常规应用进行了概括,提出除了TA-GVHD应用以外,血液辐照可能在肿瘤和微生物杀灭等方面具有广泛应用前景。With the development of transfusion medicine and the mastery of blood transfusion diagnosis and treatment techniques,the application of irradiated blood products in our country is gradually increasing.In recent years,the proportion of blood transfused byγ-rays has been increasing.In some foreign countries,the application rate of blood irradiated by radiotherapy is as high as 95%.At present,it is still in the promotion stage in China.This article summarizes the commonly used methods of blood irradiation,including the choice of irradiation source,the core dose and common irradiation targets,compares the difference of different irradiation methods,and generalizes the common application of blood irradiation.It is proposed that in addition to TA-GVHD application,blood irradiation may have a broad prospects for cancer therapy and microbial killing.

关 键 词：血液辐照 辐照源 辐照剂量 辐照对象 

分 类 号：R457.1[医药卫生—治疗学]