3%高渗盐水滴鼻治疗婴儿毛细支气管炎鼻塞的疗效观察  

Efficacy of 3% Hypertonic Saline Nasal Drip in the Treatment of Infants with Bronchiolitis and Nasal Obstruction

作　　者：沈仁 郑博 周艳 Shen Ren;Zheng Bo;Zhou Yan(Yuhuan People's Hospital,Zhejiang Yuhuan 317600,China)

机构地区：[1]玉环市人民医院

出　　处：《儿科药学杂志》2019年第12期18-20,共3页Journal of Pediatric Pharmacy

摘　　要：目的:探讨3%高渗盐水滴鼻治疗婴儿毛细支气管炎鼻塞的临床疗效。方法:将108例诊断为毛细支气管炎同时合并鼻塞的婴儿随机分为观察组和对照组各54例。在相同综合治疗的基础上,观察组给予3%高渗盐水滴鼻,每次1滴,每日3次,对照组给予0. 9%生理盐水滴鼻,每次1滴,每日3次,直到患儿鼻塞症状消失为止,比较两组患儿鼻塞消失时间、呼吸频率恢复正常时间、吸气三凹征消失时间及治疗后24 h、48 h、72 h睡眠质量评分,并比较两组患儿喂养量下降发生率。结果:观察组与对照组患儿鼻塞消失时间分别为(3. 68±1. 58) d、(4. 92±1. 99) d,呼吸频率恢复正常时间分别为(3. 86±1. 38) d、(4. 55±1. 42) d,观察组均短于对照组(P均<0. 05);观察组和对照组吸气三凹征消失时间分别为(2. 96±1. 08) d、(3. 06±1. 10) d,差异无统计学意义(P>0. 05);两组患儿治疗后48 h睡眠质量评分分别为(1. 86±0. 48)分、(2. 25±0. 62)分,72 h评分分别为(0. 86±0. 43)分、(1. 16±0. 56)分,观察组优于对照组(P均<0. 05);两组患儿喂养量下降30%以上发生率分别为35. 19%、57. 41%,观察组低于对照组(P<0. 05)。结论:3%高渗盐水滴鼻治疗婴儿毛细支气管炎鼻塞症状疗效明显,值得临床推广应用。Objective: To investigate the clinical efficacy of 3% hypertonic saline nasal drip in the treatment of infants with bronchiolitis and nasal obstruction. Methods: A total of 108 infants diagnosed as bronchiolitis and nasal obstruction were extracted to be randomly divided into the observation group( n = 54) and control group( n = 54). On the basis of the same comprehensive treatment,the observation group was given 3% hypertonic saline nasal drip,1 drop each time,3 times a day,and the control group was given 0. 9%physiological saline nasal drip,1 drop each time,3 times a day,until the nasal obstruction disappeared. The disappearance time of nasal obstruction,the recovery time of respiratory rate,the disappearance time of three concave sign,and the sleep quality scores at 24 h,48 h and 72 h after treatment of two groups were compared,the incidence of decreased feeding in two groups were recorded. Results: The disappearance time of nasal obstruction in the observation group and the control group were respectively( 3. 68± 1. 58) d and( 4. 92±1. 99) d,the recovery time of respiratory rate were respectively( 3. 86±1. 38) d and( 4. 55±1. 42) d,the observation group was shorter than the control group( P< 0. 05). The disappearance time of three concave sign in the observation group and the control group were respectively( 2. 96 ±1. 08) d and( 3. 06±1. 10) d,without any statistically significant difference( P>0. 05). The sleep quality scores at48 h of two groups were respectively( 1. 86 ± 0. 48) points and( 2. 25 ± 0. 62) points,and the sleep quality scores at 72 h were respectively( 0. 86±0. 43) points and( 1. 16± 0. 56) points,the observation group was better than the control group( P< 0. 05). The incidence of decreased feeding >30% in two groups were 35. 19% and 57. 41%,respectively,and the observation group was lower than the control group( P < 0. 05). Conclusion: The clinical efficacy of 3% hypertonic saline nasal drip in the treatment of infants with bronchiolitis and nasal obstruction is significant,which i

关 键 词：高渗盐水 毛细支气管炎 鼻塞 婴儿 

分 类 号：R725.6[医药卫生—儿科]